An overview of agrifood and veterinary biotechnology projects currently developed by the Spanish biotech industry Spanish Green Biotech Pipeline 2015 Spanish Green Biotech Pipeline INGREDIENTS, ADDITIVES AND PROBIOTICS V eterinary - A nim a l H ea l th Respiratory and pulmonary system 4% Musculoskeletal disorders 13% Autoimmune & inflammation 13% 21% Digestive system 25% Parasitic diseases 33% Infectious diseases * Company Name or description Indication / Property Aplications AB-Biotics AB-Prociscare Probiotic formula with lactic acid bacteria and cranberry extract for treating and preventing recurrent urinary tract infections (UTI) such as cystitis AB-Biotics AB-Immuno Probiotic formula with a specific functional effect for maintaining digestive health, enhancing systemic immunity and stimulating immunoglobulin production Food supplement, food ingredient AB-Biotics AB-Dentisani Probiotic formula which acts as a shield against caries, preventing the growth of caries-associated bacteria AB-Biotics AB-Gingilac Probiotic formula which improves biofilm formation by healthy oral flora, for optimal gum health AB-Biotics IronKid AB-Biotics R&D Validation Register Patent Available in the market 4 4 4 4 4 4 4 Oral care products 4 4 4 4 Food supplement, oral care products 4 4 4 4 Food supplement which contributes to the normal growth and development of children, with a special focus on their mental and cognitive development, containing AB-Fortis, DHA, Food supplement vitamins and iodine 4 4 4 4 4 IronLact Food supplement designed to meet the needs of women during the lactation period and their babies, containing AB-Fortis, DHA, minerals and vitamins Food supplement 4 4 4 4 4 AB-Biotics IronGest Food supplement designed to meet the needs of pregnant women and their babies, containing AB-Fortis, DHA, minerals and vitamins Food supplement 4 4 4 4 4 AB-Biotics AB-Life Forte Probiotic formula combining AB-Life strains (which reduces total cholesterol levels by 12% on average) and Monacolin K to enhance total cholesterol and LDL-cholesterol reduction Food supplement 4 4 4 4 4 AB-Biotics AB-Life Plus Probiotic formula combining AB-Life strains (which reduces total cholesterol levels by 12% on average) and an omega-3 source (Alpha-Linolenic Acid) to enhance total cholesterol, LDL-cholesterol and Triglycerides reduction 4 4 4 4 4 AB-Biotics AB-Intimus Probiotic able to survive in an inflamed vaginal mucosa and restore the vaginal ecosystem and a healthy vaginal pH, useful to prevent vaginal infection recurrence. It can be used in Vaginal care products co-therapy treatments with anti-mycotics 4 4 4 4 4 AB-Biotics AB-Kolicare Probiotic formula for the treatment of infantile colic, which significantly reduces excessive crying in colicky infants according to clinical data Dairy products, infant formula. Capsules, drops, sachets 4 4 4 4 4 AB-Biotics I3.1 The first probiotic formula which produces a global improvement of quality of life in IBS patients, according to published clinical data Pharma: capsules or sachets 4 4 4 4 AB-Biotics AB-Dentalac The first probiotic specifically designed to fight the oral pathogens causing the most common oral diseases: caries, gingivitis and bad breath Food supplement, chewing gums, oral care products, syringes 4 4 4 4 4 AB-Biotics AB-Fortis Patented micro-encapsulation system that allows to deliver 100% of the iron CDR in a single dose, with high bioavailability and no adverse effects in taste or during the digestion Dairy industry and nutritional supplements containing iron and vitamins 4 4 4 4 4 AB-Biotics AB-Life Probiotic formula which reduces total cholesterol levels by 12% on average, according to published clinical data Food supplement, dairy products, beverages 4 4 4 4 4 ALGAENERGY PhycoAlgae® PhycoAlgae® is a phycobiliprotein isolated from Spirulina platensis. It has a high absorptivity capacity and an intense blue colour which makes it suitable for use as a dye due to its staining ability. Its significant antioxidant properties make Phycocyanin a product of great interest Functional ingredients, Food & Beverages 4 4 ALGAENERGY AlgaeFood® Strains and extracts. Functional foods Functional ingredients 4 4 4 4 4 ALGAENERGY AlgaeFood® High level of polyunsaturated fatty acid, w3 type (EPA, DHA and ARA), proteins (essential aminoacids), vitamins, carotenoids Oils and fats / Others / Natural Products 4 4 4 4 4 Bioibérica Oralvisc Metabolic Arthritis 4 4 4 4 4 Bioibérica Mucopolysaccharides Food supplement ingredient for joints APIs (Active Pharmaceutical Ingredients) 4 4 4 4 Bioibérica B-2cool (Native Type II Collagen) Food supplement ingredient for joints APIs (Active Pharmaceutical Ingredients) 4 4 4 4 Bioibérica Mobilee Helps keep hyaluronic acid concentrations within a healthy range, thereby promoting comfortable joint mobility and reducing stiffness APIs (Active Pharmaceutical Ingredients) 4 4 4 Bioibérica Hyaluronic Acid Osteoarthritis treatment APIs (Active Pharmaceutical Ingredients) 4 4 4 4 Bioibérica Glucosamine Osteoarthritis treatment APIs (Active Pharmaceutical Ingredients) 4 4 4 4 Bioibérica Chondroitin Sulfate Osteoarthritis treatment APIs (Active Pharmaceutical Ingredients) 4 4 4 4 Bioibérica Hialsorb Sport Cream for the nutrition of athletes’ joints Sport Nutrition 4 Bioibérica Artroactive Food supplement recommended for athletes who wear down their articular cartilage Sport Nutrition 4 Bioibérica Tendoactive Food supplement recommended for tendon pain Sport Nutrition 4 Bioibérica Inmunactive Food supplement with nucleotides to help stimulate the immune system Sport Nutrition 4 BIOPOLIS Probiotics with specific activity: Metabolic syndrome Bifidobacterium lactis BPL1 Metabolic syndrome Food supplement / Food / Pharma 4 4 4 4 4 BIOPOLIS Bioactive peptides in cocoa Preventing Alzheimer and hypertension; confirmation of benefit in final product Sugar, cocoa and chocolate 4 4 4 4 4 BIOPOLIS Probiotics with specific activity: Immune system Bifidobacterium breve CNCM I-4035, Lactobacillus Active immune system paracasei CNCM I-4034, Lactobacillus rhamnosus CNCM I-4036 Food supplement / Food industry / Pharma 4 4 4 4 BIOPOLIS Probiotics with specific activity: Intestinal inflammation Bifidobacterium longum ES1 Anti-inflammatory effects Food supplement / Food industry /Pharma 4 4 4 4 4 BIOPOLIS Prebiotics Dairy industry / Bakeries / Mineral water and soft drink bottlers 4 4 4 BIOPOLIS Microorganisms and compounds as biopreservatives Improving a product’s useful life and organoleptic and microbiological quality using microorganisms Fish processing and preservation 4 4 4 4 Food supplement Gastrointestinal health improvement; confirmation of benefit in final product 4 4 4 4 BIOSEARCH PF1® Carob Extract high in non hydrolysable condensed tannins obtained by aqueous extraction system without using ethanol or organic solvents for cholesterol management Medical Device IIb / Dietary supplements 4 4 BIOSEARCH HYDROLIV PLUSTM Hydroxytyrosol (≥15%) extract from olive fruits with a strong antioxidant character Olive / seed oils industry / Dairy industry / Beverage industry / Bakeries / Meat /Fish industry / dietary supplements 4 4 BIOSEARCH EXXENTIA® Hops Dry Extract (Humulus lupulus L.) standardised in 8-Prenylnaringenin, 8-PN to alleviate menopausal discomforts Women Health / Dietary supplements 4 BIOSEARCH CARONOSITOL® D-chiro-inositol (DCI) from Carob for Polycystic Ovary Syndrome (PCOS) Women Health / Dietary supplements 4 4 4 4 4 BIOSEARCH HEREDITUM® Probiotics isolated from human breast milk for the treatment of lactational mastitis Women Health / Dietary supplements 4 4 4 4 4 BIOSEARCH HEREDITUM® Probiotics isolated from human breast milk for the prevention of infant infection Infant nutrition / Dietary supplements 4 4 4 4 4 BIOSEARCH EUPOLY-3® LC-Omega 3 oil (powder, emulsion and oil) for functional foods and nutraceuticals, with excellent organoleptic properties Olive / seed / Dairy industry / Beverage industry / Bakeries / Meat / Fish industry / dietary supplements / Infant nutrition 4 ESTEVE Gama Diabalance Products to facilitate life and care of people with diabetes in their daily lives Diabetic nutrition 4 4 4 4 4 ESTEVE Triptomax Food supplement recommended during periods of stress Nutrition 4 4 4 4 4 FECYT Probiotic New probiotics with antibacterial properties to prevent caries Oral care products / Food supplement 4 4 Fundacion MEDINA Natural preservatives Extracts with antimicrobial activity Food Manufacture 4 LEITAT Natural derived ingredients Extracts from Mediterranean Flora with certain functionalities which could be used in food (antimicrobial, antioxidant, etc.) Food additives, feed additives, supplements 4 LEITAT Enzymatic interesterification of fats and oils, and fat crystallisation Improve the nutritional profile of food products Oils and fats / Dairy industry / Sugar, cocoa and chocolate 4 Lipopharma Cardionesa (Cardionnaise) Therapeutics No cholesterol, and it lowers both blood pressure and the levels of triglycerides Sauce manufacturers 4 NATAC Omega-3 Highly concentrated omega-3 products with low content of phytanic acid NATAC Olive extracts NATAC NATAC 4 4 4 4 4 4 4 4 4 4 Oleanolic acid (98% purity), maslinic acid, hydroxytyrosol (20%). ALLOLIVE full plant profile olive extract Nutraceuticals / Olive / Seed oils industry / Dairy industry / Beverage industry / Bakeries / Meat /Fish industry / dietary supplements 4 4 4 4 4 Functional lipids Olive oil concentrates in polyphenols as hydroxytyrosol, triterpenoids, sterols, etc. Nutraceuticals / Olive / Seed oils industry / Dairy industry / Beverage industry / Bakeries / Meat /Fish industry / dietary supplements 4 4 4 4 4 Herbal extracts Innovative herbal ingredients 4 4 4 4 4 4 4 Seprox Biotech Hydroxytyrosol, hydroxytyrosol acetate and DOPAC Enhanced oil stability and protection of low-density lipoprotein (LDL) from oxidative damage Oils and fats / Dairy industry / Mineral water and soft drink bottlers 4 Seprox Biotech Hydroxytyrosol, hydroxytyrosol acetate and DOPAC Protection against colon cancer and reduction of contamination by pathogens in human food products Meat industry / Fish processing and preservation / Fruit and vegetable processing and preservation / Dairy industry 4 Seprox Biotech Hydroxytyrosol, hydroxytyrosol acetate and DOPAC Reduction of the oxidising effects of free iron and heme in meat Meat industry 4 Seprox Biotech Hydroxytyrosol Food suplements , health suplements and cosmetic Natural antioxidant of olive oil 4 4 VETERINARY www.asebio.com Spanish Bioindustry Association ASEBIO, the Spanish Bioindustry Association, encompasses over 280 firms, associations, foundations, universities, technology and research centers which carry out activities directly or indirectly related to biotechnology. Around 550 companies research and develop products in the Spanish biotechnology sector. The wide number of associates makes ASEBIO the most appropriate meeting platform to face up the challenges of developing the biotechnology sector in Spain. Regulatory to R&D Preclinical Phase I Phase II Phase III Ready Market Studies location Company Product Indication Therapeutic areas Bioibérica Calmurofel Feline idiopathic cystitis Autoimmune & Inflammation Bioibérica Pro-Enteric Symptomatic treatment of diarrhoea Digestive System Bioibérica Dysgen DNA chip and a blood sample to evaluate the genetic predisposition of dogs of the Labrador Retriever breed to develop hip dysplasia Musculoskeletal Disorders Bioibérica Cosequin Powder / Cats / HA Chondroprotective drug being their main ingredients: Chondroitin sulphate and Glucosamine Musculoskeletal Disorders Bioibérica CondroVet Taste Chondroprotective specially recommended for dogs and cats with joint injuries and degenerative processes of the articular cartilage Musculoskeletal Disorders Bioibérica Feed Impromune: Nutritional Supplement recommended for dogs and cats to optimise the immune response for increased efficiency of the innate and the adaptive immune systems Autoimmune & Inflammation Bioibérica Feed Entero-Chronic: Nutritional supplement which helps maintaining intestinal functions Digestive System Bioibérica Feed DenaMarin: Nutritional supplement designed to provide specific nourishment to help liver function in cases of acute liver insufficiency in dogs and cats Digestive System Bioibérica Feed Denosyl: Nutritional supplement with the specific nutritional purpose of enhancing liver function in case of liver failure in dogs or cats Digestive System Ingenasa INgechip Allergies Allergen especific IgE levels detection in canine sera samples, based on microarray technology Autoimmune & Inflammation Ingenasa IBDV-VLP Gumboro Disease Infectious Diseases Ingenasa PPV-VLP Porcine Parvovirus Infectious Diseases MSD MCR (Zuprevo) Prevention of respiratory diseases in pigs Respiratory and Pulmonary system MSD ISO (CBPI oral) Treatment of flea and tick infestation in dogs Parasitic Diseases Laboratorios LETI Protein Q Canine leishmaniasis Parasitic Diseases Bionaturis BNT004 Nematode in livestock Parasitic Diseases Ingenasa INGEZIM RVFV Diagnostic of Rift Valley fever virus (RVFV) in ruminants Infectious Diseases Bionanoplus Antigen delivery for vaccines Encapsulation of antigens with a polymer to increases the vaccination efficacy Infectious Diseases Bionaturis BNT005 Canine leishmaniasis Parasitic Diseases Biopolis Probiotics and functional ingredients Porcine, bovine, poultry, pet-food Infectious Diseases / Digestive System DIOMUNE BABEINMUNE Babebiosis Infectious Diseases / Parasitic Diseases DIOMUNE MASTIPRO Mastitis Infectious Diseases FECYT FMD Foot-and-mouth disease Infectious Diseases <<<<<<<<<<<< Spain <<<<<<<<<<<< <<<<<<<<<<<< Spain <<<<<<<<<<<< <<<<<<<<<<<< <<<<<<<<<<<< Spain <<<<<<<<<<<< <<<<<<<<<<<< <<<<<<<<<<<< <<<<<<<<<<<< Europe <<<<<<<<<<<< Europe <<<<<<<<<<<< Europe <<<<<<<<<<<< Spain <<<<<<<<<<<< Spain Europe <<<<<<<<<< Latam <<<<<<<< Europe <<<<<< <<<< Europe <<<< Worldwide <<<< Spain <<<< Spain <<<< Europe / <<<< Latin America MSD HIP (CBPI topical) Treatment of flea and tick infestation in dogs and cats Parasitic Diseases << *Based on data provided by ASEBIO associated companies. MAY 2015. www.asebio.com Spain An overview of agrifood and veterinary biotechnology projects currently developed by the Spanish biotech industry Spanish Green Biotech Pipeline 2015 Spanish Green Biotech Pipeline * FOOD SAFETY AND SUBSTANCE DETECTION Company Name or description Biomedal Biomedal Biomedal Biomedal Biomedal Biomedal Biomedal Biomedal Biomedal Biomedal AlerTox Sticks Fish GlutenTox Pro Surface Food analysis services Gluten analysis services GlutenTox READER GlutenTox Home GlutenTox Pro GlutenTox ELISA Competitive GlutenTox ELISA Sandwich GlutenTox Sticks Plus BIOPOLIS FECYT Ingenasa LEITAT OWL SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS SISTEMAS GENÓMICOS Indication / Property R&D Validation Register Patent in Available the market Food producers of all types 4 Food producers of all types and handlers 4 4 4 Food producers of all types 4 4 4 Food producers of all types 4 4 4 Any food industry that performs gluten tests using GlutenTox Sticks 4 4 4 Celiac 4 4 4 Food producers of all types and handlers 4 4 4 Food producers of all types 4 4 4 Food producers of all types 4 4 4 Food producers of all types 4 4 4 Aplications Test for allergen detection (fish) Test for gluten detection in surfaces Broad portfolio of food analyses (allergens, physical-chemical, microbiological, etc.) Gluten analysis services. ISO 17025 certification Immunochromatographic strip reader Rapid test for gluten detection Test for gluten detection ELISA assay for quantification of gluten in food samples suitable for hydrolysed samples ELISA assay for quantification of gluten in food samples Immunochromatographic strips for detecting gluten in foods accurate detection of this type of microorganism to minimise health risks due to Isolation and identification of altering and pathogenic microorganisms Rapid, contamination at the various stages of the process Biological Control Biopreservatives for fresh-cut products; fruits and vegetables INgezim Soy Detection of soy residues in food samples In vitro tests for toxicity, safety, ADME and plasma efficacy Genotoxicity, phototoxicity, hepatotoxicity, ADME Metabolics and Lipidomics analysis Lipids and metabolites identification AutentiGEN® SG Kits®-Alicyclobacillus Kit for the detection of Alicyclobacillus spp. and Alicyclobacillus acidoterrestris by Real-Time PCR Self Analysis Products InmuTest Food Intolerance Study Genomic identification Service of Microorganisms Microbiological Analysis AutentiGEN®-Quant Porcino Quantification method of porcine DNA in meat matrices AutentiGEN®-Quant Equino Quantification method of Equine DNA in food Verify of the IBERIAN BREED Service to verify the genetic origin of animals and products of the IBERIAN BREED Services to detect food allergens. These services are based on the latest DNA technologies and immunoanalysis, AGROFOOD which verify the presence or absence of allergen ingredients in any food type AutentiGEN®-Equino Horse DNA detection by Real-Time PCR® Food producers of all types 4 4 Fruits and Vegetables processing and preservation Food safety Food producers of all types Food producers of all types Fruit juices, concentrates as well as tomato-based products Applicable to all industries Applicable to all industries Applicable to all industries Applicable to all industries Applicable to all industries Applicable to all industries 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 Applicable to all industries 4 4 4 Applicable to all industries 4 4 4 4 4 4 BIOPRODUCTS, BIOPROCESSES ANT OTHER TECHNOLOGIES Company Name or description AC-Gen Reading Life WineSeq Indication / Property Aplications Wine Industry Replaces the conventional pesticide to be applied to crops against pests which cause great economic impact as whitefly, thrips, aphids, spider, mites, and many other pests Ecologically certified product with excellent results in terms of agricultural performance increase of any kind of crop AGROCODE Biopesticides from organic and natural origin Quality control Extraction process development biopesticides from plant extracts and secondary metabolites of different microorganisms ALGAENERGY AGRIALGAE High quality agricultural biostimulant 100% based on microalgae enzymatic hydrolysis Bioibérica Flyral Bioibérica Suzukii Trap Bioibérica Dacus Trap Bioibérica Cera Trap Bioibérica Armurox Bioibérica Optimus Bioibérica AminoQuelant Bioibérica Terramin Bioibérica StressSal Bioibérica Inicium Bioibérica Terra-Sorb BIOPOLIS Probiotics development for feed BIOPOLIS Process enhancement and optimisation BIOPOLIS Assessment of waste and byproducts BIOPOLIS Characterisation of the enzyme profile in commercial products Functional evaluation and validation (in vitro and in vivo) of functional ingredients and functional foods Biological Attractants: Ecological bait formulated based on hydrolysed proteins specifically selected to obtain For the fruit crop fly pest produced by the Mediterranean fruit fly the maximum attractant capacity and specificity Biological Attractants: Ecological bait formulated based on hydrolysed proteins specifically selected to obtain For the fruit crop fly pest produced by Drosophila suzukii the maximum attractant capacity and specificity Biological Attractants: Ecological bait formulated based on hydrolysed proteins specifically selected to obtain For the fruit crop fly pest produced by Bactrocera oleae (Olive tree fly) the maximum attractant capacity and specificity Biological Attractants: Ecological bait formulated based on hydrolysed proteins specifically selected to obtain For the fruit crop fly pest produced by Ceratitis capitata the maximum attractant capacity and specificity Plant protection: Dual-action product that creates a physical barrier under the cuticle and activates plant endogenous defense mechanisms Plant protection (resistance to biotic stress): Dual-acting formulation: it increases resistance to biotic stress caused by the attack of certain pathogens (fungus) and increases tolerance to abiotic stress (adverse climatic causes, primarily) Bioavailable Nutrition: Products based on L-α-amino acids from Enzymatic Hydrolysis and different chemical elements Biostimulant: Terramin® is certified for use in organic farming in Andalusia as it contains amino acids derived from enzymatic hydrolysis Biostimulant: STRESSAL® is an osmotic regulator that enhances tolerance to salt stress. STRESSAL® activates certain physiological processes that minimise the negative effects of excess salinity on plants (lost productivity, increased water consumption, etc.) Biostimulant: The low molecular weight peptides of Inicium® activate the proteins that act on stress related to transplanting Biostimulant: Increases plant photosynthesis activity and chlorophyll content Addition to a product’s formulation of living microorganisms that are validated as beneficial for health; Feed confirmation of benefit in final product Solution to production problems, with possibility of scaling solutions up to industrial scale to test efficacy Food producers of all types Pursuit of zero waste and value-added use of byproducts in the same or other industries, reducing costs and Food producers of all types tapping new revenue sources Improvement and optimisation of enzymatic processes by selecting the commercial product that offers the Dairy industry / Bakeries / Sugar, cocoa and chocolate best yield on the basis of customer needs BIOPOLIS 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 Meat industry / Dairy industry / Bakeries / Alcoholic beverages 4 Food producers of all types Food producers of all types Food producers of all types Food producers of all types APIs (Active Pharmaceutical Ingredients) Production of biological control agents as fungi Integrated pest management of red palm weevil To promote plant health 4 4 4 4 LEITAT LEITAT Microbiological treatment of pollutants including isolation of Biotechnological treatment of pollutants using new adapted consortia new consortia Agricultural waste valorisation Production of ingredients from agricultural wastes Collagen and keratin hydrolysis Production of protein hydrolisates LEITAT Biofilms Study of biofilm formation and validation of technologies for biofilm removal LEITAT Microencapsulation Protection of active ingredients / Controlled release / Avoidance of organoleptic problems LEITAT Plasma for sanitising Sanitising surfaces for food LEITAT Reuse of byproducts and coproducts: production of functional products Production of products for the cosmetic / food / pharmaceutical industry and for animal feed LEITAT Enzymatic interesterification of fats and oils, and fat crystallisation Strains improvement Production of baits Production of crop agents Production of soil improvers 4 4 4 4 4 4 4 4 4 4 4 4 4 4 Treatment of soils and wastewaters 4 Ingredients for food and feed Fertilizers, cosmetics, feed, etc. Oils and fats / Dairy industry / Sugar, cocoa and chocolate / Fish processing and preservation / Fruit and vegetable processing and preservation Dairy industry / Sugar, cocoa and chocolate / Fruit and vegetable processing and preservation / Bakeries Oils and fats / Dairy industry / Sugar, cocoa and chocolate / Fish processing and preservation / Fruit and vegetable processing and preservation Oils and fats / Dairy industry / Sugar, cocoa and chocolate / Fish processing and preservation / Fruit and vegetable processing and preservation 4 4 Improve the nutritional profile of food products Oils and fats / Dairy industry / Sugar, cocoa and chocolate 4 Strains improvement without genetic modification (random mutagenesis and/or induction of natural transfer) Production of baits for insect control (protein hydrolsates as insect attractants) Production of crop agents based on antimicrobial peptides Production of soil improvers based on peptides and amino acides Genetic fingerprinting of individuals, varieties and populations. Identification of varieties and phylogenetic relationships. Analysis of genetic diversity in natural populations and breeding. Improving plant genetics. Identification of genes of agronomic interest (disease resistance, increased production, improved organoleptic and nutritional properties, etc.) Food and environmental application Pest fight Fertilizers Fertilizers 4 4 4 Applicable to all industries. Crop improvement 4 4 Metabolites for plant abiotic stress protection Crop treatment to prevent abiotic stress and increase yields Food producers of all types 4 4 4 Validation of biostimulants Improving the quality and shelf life of fruit and vegetables Fruit and vegetable processing and preservation 4 4 4 Elicitor to stimulate plants’ innate immunity Crop treatment to prevent diseases and increase yields Fruit and vegetable processing and preservation 4 4 4 Parque Científico Tecnológico Aula Dei Molecular Biology laboratory www.asebio.com Spanish Bioindustry Association ASEBIO, the Spanish Bioindustry Association, encompasses over 280 firms, associations, foundations, universities, technology and research centers which carry out activities directly or indirectly related to biotechnology. Around 550 companies research and develop products in the Spanish biotechnology sector. The wide number of associates makes ASEBIO the most appropriate meeting platform to face up the challenges of developing the biotechnology sector in Spain. LEITAT 4 4 Ensure that fermentation takes place at the proper time and with the selected microorganisms, ensuring uniformity between product batches, control over fermentation time and final product quality LCMS & NMR analytical platform Microbial fermentation & scale up platform High Throughput Screening of biotechnological products Bioactive molecule discovery Platform 600 L, 2,000 L and 12,000 L fermenters Dry formulation based on biological control agents as fungi to control pest without water Biological product base on Beauveria bassiana against red palm weevil Use of endophytic fungi Micro nanospheres for release injectable products of peptide MEDchemistry MEDmicro MEDScreen MEDiscovery Fermentation and downstream processes Solid fermentation processes Dry formulation based on Bb203 Phoemyc certification of biological VivaCell Biotechnology Scientific activity of foods, extracts and España functional ingredients 4 4 4 Fundacion MEDINA Fundacion MEDINA Fundacion MEDINA Fundacion MEDINA Gadea Biopharma GLEN BIOTECH GLEN BIOTECH GLEN BIOTECH GP-PHARM Available in the market 4 4 Dairy industry / Sugar, cocoa and chocolate Fermentation starters Plant Response Biotech Plant Response Biotech Plant Response Biotech 4 Functionality confirmation in the final product (oxidative stress, obesity, neurodegeneration, diabetes, antimicrobial infection, etc.) BIOPOLIS LEITAT LEITAT LEITAT LEITAT R&D Validation Register Patent 4 4 4 4 4 4 4 4 4 Studies in vitro and in vivo of the impact on obesity and metabolic syndrome, ageing, cardiovascular system, Applicable to all industries immune system, neuroprotection and nutricosmetics 4 FEED Company Name or description Indication / Property ALGAENERGY Bioibérica AlgaePiscis® Snacks-Goodogs Caprice & Treat Nucleoforce Piglets / Horses / Fish / Cows / Poultry / Dogs / Salmonids / Shrimps Palbio 50RD / 62SP / 360L Hemicellulolytic enzymes (xylanase) HEREDITUM® EXXENTIA® HYDROLIV PLUS™ EXXENTIA® Camelina husks Camelina meal Functional protein hydrolysates enriched in active peptides HP-40 Cividox Natacalm MAC-60 Hydroxytyrosol, hydroxytyrosol acetate and DOPAC Fish & livestock. High level of polyunsaturated fatty acid, w3 type (EPA, DHA and ARA), proteins, vitamins, and carotenoids Snacks for dogs with porcine fresh meat Bioibérica Bioibérica BIOPOLIS BIOSEARCH BIOSEARCH BIOSEARCH BIOSEARCH Camelina Company España Camelina Company España LEITAT NATAC NATAC NATAC NATAC Seprox Biotech R&D Validation Register Patent in Available the market 4 4 4 4 4 4 4 4 4 4 Nucleotides content for insufficient novo or endogenous synthesis (necessary for development of tissues with a high cell replication rate like reproductive, immune and intestinal tissues) 4 4 4 4 4 Aids in increasing feed intake and contributes to the development of the intestinal mucosa thanks to its exceptional characteristics and high digestibility Faster livestock growth with lower feed costs through improved feed digestibility and the consequent increase in yields Probiotics strains for improvement of weight gain in piglets Artichoke extract for liver protection Hydroxytyrosol ( ≥15%) from olive fruit with strong antioxidant character Plant extracts with different functionalities for healthcare (cardiovascular, digestive, immune system, stress, antioxidants, etc.) Animal feed - high vegetable fiber content Animal feed - high protein content. Omega 3 content For feed additives and other applications with antioxidant, antimicrobial, anti-inflammatory Hepatic protection Antioxidant, vitamin E enhancer. Meat quality Swine and ruminants Aquaculture, concentrated olive oil, economical benefits due to intestinal protection Reduction of contamination by pathogens in animal food products 4 4 4 4 *Based on data provided by ASEBIO associated companies. MAY 2015. www.asebio.com 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4
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