1. Healthcare

Curriculum Vitae
PERSONAL INFORMATION
Arno Hoes
WORK EXPERIENCE
2010–Present
Chair
Julius Center for Health Sciences and Patient Care, University Medical Center Utrecht, (Netherlands)
2007–2011
Research manager
Julius Center for Health Sciences and Patient Care, University Medical Center Utrecht, (Netherlands)
1998–Present
Professor of Clinical Epidemiology and General Practice
Julius Center for Health Sciences and Patient Care, University Medical Center Utrecht, (Netherlands)
1996–1998
Associate professor
Julius Center for Health Sciences and Patient Care, University Medical Center Utrecht, (Netherlands)
1991–1996
assistant professor
Erasmus University Medical School, Department of Epidemiology and Biostatistics, Rotterdam,
(Netherlands)
EDUCATION AND TRAINING
1978–1986
Medical Degree
St Radboud Medical Center / Radboud University, Nijmegen, (Netherlands)
–1988
Epidemology fellowship
London School of Hygiene and Tropical Medicine, (United Kingdom)
1988–1992
PhD thesis
Erasmus University, Rotterdam, (Netherlands)
ADDITIONAL INFORMATION
Expertise
Clinical epidemiology
Cardiovascular disease
Heart failure
Primary care
Publications
Bezáková N, Damoiseaux RAMJ, Hoes AW, Schilder AGM, Rovers MM, Recurrence up to 3.5 years
after antibiotic treatment of acute otitis media in very young Dutch children: survey of trial participants.
BMJ 2009; 339: 96-8.
Bijkerk CJ, Wit NJ de, Muris JWM, Whorwell PJ, Knottnerus JA, Hoes AW. Soluble or insoluble fibre in
irritable bowel syndrome in primary care? Randomized placebo-controlled trial. BMJ 2009; 339: 6135.
Bont J, Hak E, Birkhoff C, Hoes A, Verheij T. Antibiotica bij acute bronchitis en COPD-exacerbaties
met comorbiditeit. Huisarts Wet 2009; 52: 130-4.
Boonman-de Winter LJ, Rutten FH, Cramer MJ, Liem AH, Landman MJ, Stel HF van, Wit GA de,
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Arno Hoes
Rutten GE, Hessen PA van, Hoes AW. Early recognition of heart failure in patients with diabetes type
2 in primary care. A prospective diagnostic efficiency study. (UHFO-DM2). BMC Public Health 2009; 9:
479.
Boudestein LC, Rutten FH, Cramer MJ, Lammers JW, Hoes AW. The impact of concurrent heart
failure on prognosis in patients with chronic obstructive pulmonary disease. Eur J Heart Fail 2009; 11;
1182-8.
Broekhuizen BD, Sachs AP, Oostvogels R, Hoes AW, Verheij TJ, Moons KG. The diagnostic value of
history and physical examination for COPD in suspected or known cases: a systematic review. Fam
Pract 2009; 26 :260-8.
Broekhuizen BDL, Sachs APE, Hoes AW, Verheij TJM, Moons KGM. The diagnostic value of history
and physical examination for COPD [e-letter]. Fam Pract 2009;26:239-40.
Büller HR, Cate-Hoek AJ ten, Hoes AW, Joore MA, Moons KG, Oudega R, Prins MH, Stoffers HE, Toll
DB, Velde EF van der, Weert HC van; AMUSE (Amsterdam Maastricht Utrecht Study on
thromboEmbolism) Investigators. Safely ruling out deep venous thrombosis in primary care. Ann
Intern Med 2009; 150: 229-35. Comm in: Ann Intern Med. 2009;150:270-1.
Büller H, Cate-Hoek A ten, Hoes A, Joore M, Moons K, Oudega R, Prins M, Stoffers J, Toll D, Velde
EF van der, Weert H van. De huisarts kan zelf diepe veneuze trombose veilig uitsluiten. Huisarts Wet
2009; 10: 497-502.
Cate-Hoek AJ ten, Toll DB, Büller HR, Hoes AW, Moons KGM, Oudega R, Stoffers HEJH, Velde EF
van der, Weert HCPM van, Prins MH, Joore MA. Cost-effectiveness of ruling out deep venous
thrombosis in primary care versus care as usual. J Thromb Haemost 2009; 7:2042-9.
Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA, Strömberg A,
van Veldhuisen DJ, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Vahanian A,
Camm J, De Caterina R, Dean V, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K,
Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Auricchio A, Bax J, Böhm M, Corrà U,
della Bella P, Elliott PM, Follath F, Gheorghiade M, Hasin Y, Hernborg A, Jaarsma T, Komajda M,
Kornowski R, Piepoli M, Prendergast B, Tavazzi L, Vachiery JL, Verheugt FW, Zannad F; Task Force
per la Diagnosi e il Trattamento dello Scompenso Cardiaco Acuto e Cronico 2008 della Societá
Europea di Cardiologia. Linee guida ESC per la diagnosi e il trattamento dello scompenso cardiaco
acuto e cronico 2008. [Guidelines for the diagnosis and treatment of acute and chronic heart failure
2008] G Ital Cardiol (Rome) 2009;10(3):141-98; discussion 199-202.
Dickstein, K, Cohen-Solal, A, Filippatos, G, McMurray, JJV, Ponikowski, P, Poole-Wilson, PA,
Strömberg, A, Van Veldhuisen, DJ, Atar, D, Hoes, AW, Keren, A, Mebazaa, A, Nieminen, M, Priori,
SG, Swedberg, K. Erratum: ESC Guidelines for the diagnosis and treatment of acute and chronic
heart failure 2008 (Eur J Heart Fail 2008;10:933-989) Eur J Heart Fail 2009, 11: 110.
Geersing GJ, Janssen KJM, Oudega R, Bax L, Hoes AW, Reitsma JB, Moons KGM. Excluding
venous thrombo-embolism using point-of-care D-dimer tests in outpatients. a diagnostic metaanalysis. BMJ 2009;339:b2880
Geijer R, Sachs A, Verheij T, Kerstjens H, Kuyvenhoven M, Hoes A. Kwaliteit van leven bij rokers: zijn
functionele beperkingen belangrijker dan longfunctie?? Huisarts Wet 2009; 52: 39-44.
Grobbee DE, Hoes AW. Clinical Epidemiology. Principles, methods, and applications for clinical
research. Boston: Jones and Bartlett Publishers, 2009.
Groenwold RH, Donders AR, van der Heijden GJ, Hoes AW, Rovers MM. Confounding of subgroup
analyses in randomized data. Arch Intern Med 2009; 169: 1532-4.
Groenwold RHH, Hak E, Hoes AW. Pooling of confounders did not induce residual confounding in
influenza vaccination studies. Ann Epidemiol 2009; 19 6: 432-6.
Groenwold RHH, Hak E, Hoes AW. Quantitative assessment of unobserved confounding is
mandatory in nonrandomized intervention studies. J Clin Epidemiol 2009; 62: 22-8.
Groenwold RHH, Hoes AW, Hak E. Impact of influenza vaccination on mortality risk among the
elderly. Eur Resp J 2009; 34: 56-62.
Helsper CW, Smeets HM, Numans ME, Knol MJ, Hoes AW, de Wit NJ.Trends and determinants of
adequate gastroprotection in patients chronically using NSAIDs. Pharmacoepidemiol Drug Saf 2009;
18: 800-6.
Hoes AW, Washbrook E, Jackson R. Cardiovascular risk management series: 3. Identifying high risk
patients. Prim Care Cardiovasc J 2009; 1: 41-7.
Kelder JC, Rutten FH, Hoes AW. Clinically relevant diagnostic research in primary care: The example
of B-type natriuretic peptides in the detection of heart failure. Fam Pract 2009;26:69-74.
Rovers MM, Hoes AW, Klinkhamer S, Schilder AG. Influence of single-trial results on clinical practice:
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example of adenotonsillectomy in children. Arch Otolaryngol Head Neck Surg 2009; 135: 970-5.
Smeets HM, Wit NJ de, Delnoij DM, Hoes AW. Patient attitudes towards and experiences with an
intervention programme to reduce chronic acid-suppressing drug intake in primary care. Eur J Gen
Pract 2009;15:219-25
Bijkerk R, Wit N de, Muris J, Whorwell P, Knottnerus A, Hoes A. Oplosbare of niet-oplosbare vezels:
Wat werkt beter bij het prikkelbaredarm-syndroom? Huisarts Wet 2010; 53:195-202.
Boonacker CWB, Hoes AW, Dikhoff MJ, Schilder AGM, Rovers MM. Interventions in health care
professionals to improve treatment in children with upper respiratory tract infections. Int J Pediatr
Otorhinolaryngol 2010; 74: 1113-21.
Bosch M, Wensing M, Bakx JC, Weijden T van der, Hoes AW, Grol RPTM. Current treatment of
chronic heart failure in primary care; still room for improvement. J Eval Clin Pract 2010; 16: 644-50.
Bosch M, Wensing M, Bakx C, Weijden van der T, Hoes AW, Grol R. Behandeling van chronisch
hartfalen. Huisarts Wet 2010;53: 667-70.
Broekhuizen BD, Sachs AP, Hoes AW, Moons KG, Berg JW van den, Dalinghaus WH, Lammers E,
Verheij TJ. Undetected chronic obstructive pulmonary disease and asthma in people over 50 years
with persistent cough. Br J Gen Pract 2010;60:489-94.
Bruins Slot MH, Reitsma JB, Rutten FH, Hoes AW, van der Heijden GJ. Heart-type fatty acid-binding
protein in the early diagnosis of acute myocardial infarction: a systematic review and meta-analysis.
Heart 2010;96:1957-63.
Damoiseaux R, Bezáková N, Hoes A, Schilder A, Rovers M. Antibiotica bij kinderen met otitis media
acuta verhogen de kans op een recidief. Huisarts Wet 2010; 53:101-4.
Dekker MS, Mosterd A, Hof AWJ van ‘t, Hoes AW. Novel biochemical markers in suspected acute
coronary syndrome: Systematic review and critical appraisal. Heart 2010; 96: 1001-10.
Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJV, Ponikowski P, Poole-Wilson PA, Strömberg
A, Veldhuisen DJ van, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Swedberg K.
Erratum: ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008 (Eur
Heart J 2008; 29: 2388-2442). Eur Heart J 2010; 31:624.
Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJV, Ponikowski P, Poole-Wilson PA, Strömberg
A, Veldhuisen DJ van, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Swedberg K.
The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the
European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the
ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM) Corrigendum
to ‘ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008’ [Eur Heart
J 2008;29:2388–2442 and Eur J Heart Fail 2008;10:933–989]. Eur J Heart Fail, 2010;12: 416.
Dickstein K, Vardas PE, Auricchio A, Daubert JC, Linde C, McMurray J, Ponikowski P, Priori SG,
Sutton R, van Veldhuisen DJ, Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Filippatos G, FunckBrentano C, Hobbs R, Kearney P, McDonagh T, Popescu BA, Reiner Z, Sechtem U, Sirnes PA,
Tendera M, Vardas P, Widimsky P, Tendera M, Anker SD, Blanc JJ, Gasparini M, Hoes AW, Israel
CW, Kalarus Z, Merkely B, Swedberg K, Camm AJ. 2010 Focused Update of ESC guidelines on
device therapy in heart failure: An update of the 2008 ESC guidelines for the diagnosis and treatment
of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization
therapy Developed with the special contribution of the Heart Failure Association and the European
Heart Rhythm Association. Eur Heart J 2010; 31: 2677–87.
Dickstein K, Vardas PE, Auricchio A, Daubert JC, Linde C, McMurray J, Ponikowski P, Priori SG,
Sutton R, van Veldhuisen DJ, Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Filippatos G, FunckBrentano C, Hobbs R, Kearney P, McDonagh T, Popescu BA, Reiner Z, Sechtem U, Sirnes PA,
Tendera M, Vardas P, Widimsky P, Tendera M, Anker SD, Blanc JJ, Gasparini M, Hoes AW, Israel
CW, Kalarus Z, Merkely B, Swedberg K, Camm AJ. 2010 Focused Update of ESC Guidelines on
device therapy in heart failure: An update of the 2008 ESC Guidelines for the diagnosis and treatment
of acute and chronic heart failure and the 2007 ESC Guidelines for cardiac and resynchronization
therapy * Developed with the special contribution of the Heart Failure Association and the European
Heart Rhythm Association. Eur J Heart Fail 2010;12:1143-53.
Dickstein K, Vardas PE, Auricchio A, Daubert JC, Linde C, McMurray J, Ponikowski P, Priori SG,
Sutton R, van Veldhuisen DJ, Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Filippatos G, FunckBrentano C, Hobbs R, Kearney P, McDonagh T, Popescu BA, Reiner Z, Sechtem U, Sirnes PA,
Tendera M, Vardas P, Widimsky P, Tendera M, Anker SD, Blanc JJ, Gasparini M, Hoes AW, Israel
CW, Kalarus Z, Merkely B, Swedberg K, Camm AJ. 2010 Focused Update of ESC Guidelines on
device therapy in heart failure: an update of the 2008 ESC Guidelines for the diagnosis and treatment
of acute and chronic heart failure and the 2007 ESC Guidelines for cardiac and resynchronization
therapy. Developed with the special contribution of the Heart Failure Association and the European
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Arno Hoes
Heart Rhythm Association. Europace 2010;12:1526-36.
Geersing GJ, Janssen K, Oudega R, van Weert H, Stoffers H, Hoes A, Moons K. Diagnostic
classification in patients with suspected deep venous thrombosis: physicians' judgement or a decision
rule? Br J Gen Pract 2010;60:742-8.
Geersing GJ, Toll DB, Janssen KJ, Oudega R, Blikman MJ, Wijland R, Vooght KM de, Hoes AW,
Moons KG. Diagnostic accuracy and user-friendliness of 5 point-of-care D-dimer tests for the
exclusion of deep vein thrombosis. Clin Chem 2010; 56;1758-66.
Groenwold RH, Hak E, Klungel OH, Hoes AW. Instrumental variables in influenza vaccination studies:
mission impossible?! Value Health 2010; 13:132-7.
Groenwold RHH, Nelson DB, Kristin N, Hak E, Hoes AW. Sensitivity analyses to estimate the potential
impact of unmeasured confounding in causal research. Int J Epidemiol 2010; 39:107-17.
Hoes AW. The physician, the pharmacist and the MEB. In: Slijkerman DS, Ree JM van, Meijer RTW,
Breeveld EBA (ed). Evaluating Medicines. Perspectives from a european regulatory authority. (ISBN:
978 0 9564943 0 6). London: Topra publishing 2010; 46-9.
Hoes AW, Voors AA, Rutten FH, Van Lieshout J, Janssen PGH, Walma EP. NHG-Standaard
Hartfalen. Huisarts Wet 2010;7:368-89.
Hoes AW, Walma EP, Rutten FH, Twickler TB, Rohling R, Jansen RWMM, Jaarsma T, Feenstra TL,
Bouvy ML, Buskens E, De Graaff M (tot 1 september 2008), De Kok IHM, Dijkgraaf R (tot 1
september 2008), Duin M, Fischer E, Flikweert S † (tot 26 augustus 2008), Hammelburg R, Honig A,
Hulzebos E, In den Bosch HJH (tot 1 juli 2008), Janssen-Boyne J, Koers H, Kortrijk M, Ninaber PA,
Poot E (vanaf 1 juli 2008), Post PN, Rosenbrand CJGM, Schiffer AAJJ, Van Dijk JL, Van Dijk P, Van
Erp J, Van Erven L (vanaf 1 september 2008), Van Leen M, Van Lieshout J, Van Veldhuisen DJ (tot 1
juli 2008), Weerts M (vanaf 1 september 2008), Voors AA. Multidisciplinaire richtlijn Hartfalen 2010.
http://www.cbo.nl/thema/Richtlijnen/Overzicht-richtlijnen/Cardiovasculaire-aandoening/
Rutten FH, Zuithoff NP, Hak E, Grobbee DE, Hoes AW. Beta-blockers may reduce mortality and risk
of exacerbations in patients with chronic obstructive pulmonary disease. Arch Intern Med
2010;170:880-7.
Scheltens T, Beulens JW, Verschuren WMM, Boer JM, Hoes AW, Grobbee DE, Bots ML. Awareness
of hypertension: Will it bring about a healthy lifestyle? J Hum Hypertens 2010; 24: 561-7.
Scheltens T, Beus MF de, Hoes AW, Rutten FH, Numans ME, Mosterd A, Kors JA, Grobbee DE, Bots
ML. The potential yield of ECG screening of hypertensive patients: the Utrecht Health Project. J
Hypertens 2010;28:1527-33.
Smeets HM, Wit NJ de, Zuithoff NPA, Dijk PCM van, Lee APM van der, Hoes AW. A health insurance
company-initiated multi-faceted intervention for optimizing acid-suppressing drug prescriptions in
primary care; a randomized controlled trial. Arch Intern Med 2010; 170:1264-8.
Vaartjes I, Hoes AW, Reitsma JB, Bruin A de, Grobbee DE, Mosterd A, Bots ML. Age- and genderspecific risk of death after first hospitalization for heart failure. BMC Public Health 2010; 10: 637.
Wangge G, Klungel OH, Roes KCB, Boer A de, Hoes AW, Knol MJ. Interpretation and inference in
noninferiority randomized controlled trials in drug research. Clin Pharmacol Ther 2010; 88:420-3.
Wangge G, Klungel OH, Roes KCB, Boer A de, Hoes AW, Knol MJ. Room for improvement in
conducting and reporting non-inferiority randomized controlled trials on drugs: A systematic review.
PLoS ONE 2010; 5: e13550.
Aardweg, MTA van den, Boonacker CWB, Rovers MM, Hoes AW, Schilder AGM. Effectiveness of
adenoidectomy in children with recurrent upper respiratory tract infections: open randomised
controlled trial. BMJ 2011;343:d5154
Boonacker CWB, Hoes AW, Liere-Visser K van, Schilder AGM, Rovers MM. A comparison of
subgroup analyses in grant applications and publications. Am J Epidemiol 2011; 174: 219-25.
Broekhuizen BD, Sachs AP, Moons KG, Cheragwandi SA, Damsté HE, Wijnands GJ, Verheij TJ,
Hoes AW. Diagnostic value of oral prednisolone test for chronic obstructive pulmonary disorders. Ann
Fam Med 2011; 9: 104-9.
Broekhuizen BDL, Sachs A, Janssen K, Geersing GJ, Moons K, Hoes A, Verheij T. Does a decision
aid help physicians to detect chronic obstructive pulmonary disease? Br J Gen Pract 2011;61:674-9.
Bruins Slot MH, Rutten FH, Heijden GJMG van der, Geersing GJ, Glatz JFC, Hoes AW. Diagnosing
acute coronary syndrome in primary care: comparison of the physicians' risk estimation and a clinical
decision rule. Fam Pract 2011; 28: 323–8.
Bruins Slot M, Rutten F, Reitsma H, Heijden G van der, Hoes AW. The authors' reply. Heart 2011;
97:605.
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Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJV, Ponikowski P, Poole-Wilson PA, Stromberg
A, Van Veldhuisen DJ, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Swedberg K,
Vahanian A, Camm J, De Caterina R, Dean V, Funck-Brentano C, Hellemans I, Kristensen SD,
McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Auricchio A, Bax J, Bohm
M, Corrà U, Della Bella P, Elliott PM, Follath F, Gheorghiade M, Hasin Y, Hernborg A, Jaarsma T,
Komajda M, Kornowski R, Piepoli M, Prendergast B, Tavazzi L, Vachiery J-L, Verheugt FWA, Zannad
F. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. Revista
Portuguesa de Cardiologia 2011; 29: 633-99.
Geersing GJ, Janssen K, Oudega R, van Weert HC, Stoffers HE, Hoes AW, Moons KG. Deep venous
thrombosis. Br J Gen Pract. 2011;61:141.
Groenwold RH, Klungel OH, Grobbee DE, Hoes AW. Selection of confounding variables should not
be based on observed associations with exposure. Eur J Epidemiol 2011; 26: 589-93.
Groenwold RHH, Moons KGM, Peelen LM, Knol MJ, Hoes AW. Reporting of treatment effects from
randomized trials: a plea for multivariable risk ratios. Contemp Clinical Trials 2011; 32: 399-402.
Groenwold RHH, Vries F de, Boer A de, Pestman WR, Rutten FH., Hoes AW, Klungel OH. Balance
measures for propensity score methods: a clinical example on beta-agonist use and the risk of
myocardial infarction. Pharmacoepidemol Drug Saf 2011; 20: 1130-7.
Janssen KJM, Velde EF van der, Cate AJ ten, Prins MH, Weert HCPM van, Stoffers HEJH, Buller HR,
Oudega R, Hoes AW, Toll DB, Moons KGM. Optimisation of the diagnostic strategy for suspected
deep-vein thrombosis in primary care. Thromb Haemost 2011; 105: 154-60.
Kelder JC, Cowie MR, McDonagh TA, Hardman SMC, Grobbee DE, Cost B, Hoes AW. Quantifying
the added value of BNP in suspected heart failure in general practice: An individual patient data metaanalysis. Heart 2011;97:959-63.
Kelder JC, Cramer MJ, Rutten FH, Plokker HW, Grobbee DE, Hoes AW. The furosemide diagnostic
test in suspected slow-onset heart failure: popular but not useful. Eur J Heart Fail 2011; 13: 513–7.
Kelder JC, Cramer MJ, Verweij WM, Grobbee DE, Hoes AW. Clinical utility of three B-type natriuretic
Peptide assays for the initial diagnostic assessment of new slow-onset heart failure. J Card Fail
2011;17:729-34.
Kelder JC, Cramer MJ, Wijngaarden J van, Tooren R van, Mosterd A, Moons KGM, Lammers JW,
Cowie, MR, Grobbee DE, Hoes AW. The diagnostic value of physical examination and additional
testing in primary care patients with suspected heart failure. Circulation 2011; 124: 2865-73.
Oudejans I, Mosterd A, Bloemen JA, Valk MJ, Velzen E van, Wielders JP, Zuithoff NP, Rutten FH,
Hoes AW. Clinical evaluation of geriatric outpatients with suspected heart failure: value of symptoms,
signs, and additional tests. Eur J Heart Fail 2011;13:518-27.
Oudejans I, Mosterd A, Hoes AW. Diagnosis of heart failure in elderly patients: a clinical challenge-reply. Eur J Heart Fail 2011;13:1152-3.
Piepoli MF, Conraads V, Corrà U, Dickstein K, Francis DP, Jaarsma T, McMurray J, Pieske B,
Piotrowicz E, Schmid JP, Anker SD, Solal AC, Filippatos GS, Hoes AW, Gielen S, Giannuzzi P,
Ponikowski PP. Exercise training in heart failure: from theory to practice. A consensus document of the
Heart Failure Association and the European Association for Cardiovascular Prevention and
Rehabilitation. Eur J Heart Fail 2011; 13:347-57.
Putzeist M, Mantel-Teeuwisse AK, Gispen-De Wied CC, Hoes AW, Leufkens HG. Regulatory
scientific advice in drug development: Does company size make a difference? Eur J Clin Pharmacol
2011; 67: 157-64.
Scheltens T, Beus M de, Hoes A, Rutten F, Numans M, Mosterd A, Kors J, Grobbee R, Bots M. Een
elektrocardiogram bij elke patiënt met hypertensie. Huisarts Wet 2011; 54:122-7.
Smeets HM, Hoes AW, Zuithoff NPA, Dijk PCM van, Lee APM van der, Wit NJ de. A health insurance
company-initiated practice support intervention for optimizing acid-suppressing drug prescriptions in
primary care Eur J Gastroenterol Hepatol 2011; 23: 664-70.
Smeets HM, Wit NJ de, Hoes AW. Routine health insurance data for scientific research: Potential and
limitations of the Agis Health Database. J Clin Epidemiol 2011; 64; 424-30.
Velde EF van der, Toll DB, Cate-Hoek A ten, Oudega R, Stoffers HE, Bossuyt PM, Büller HR, Prins
MH Hoes AW, Moons KG, Weert HCvan. Comparing the dagnostic prformance of 2 clinical decision
rules to rule out deep vein thrombosis in primary care patients. Ann Fam Med 2011; 9: 31-6
Voors AA, Walma EP, Twickler TB, Rutten FH, Hoes AW. Multidisciplinaire werkgroep “Hartfalen
2010”. Multidisciplinaire richtlijn ‘Hartfalen 2010’. Ned Tijdschr Geneeskd 2011;155:A2957.
Wangge G, Klungel OH, Roes KC, de Boer A, Hoes AW, Knol MJ. Challenges of defining a noninferiority margin: a case study of non-inferiority randomized controlled trials of oral anti-thrombolytic
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agents for prophylaxis of venous thromboembolic events after orthopedic surgery. Trials 2011;12
Suppl 1:A32.
Zhang J; Rutten FH; Cramer MJ; Lammers JW; Zuithoff NP; Hoes AW. The importance of
cardiovascular disease for mortality in patients with COPD: a prognostic cohort study. Fam Pract
2011; 28:474-81.
Blom MT, Warnier MJ, Bardai A, Berdowski J, Koster RW, Souverein PC, Hoes AW, Rutten FH, de
Boer A, De Bruin ML, Tan HL. Reduced in-hospital survival rates of out-of-hospital cardiac arrest
victims with obstructive pulmonary disease. Resuscitation. 2012 Oct 17. pii: S0300-9572(12)00862-3.
doi: 10.1016/j.resuscitation.2012.10.009. [Epub ahead of print]
Boonacker CWB, van den Aardweg MTA, Hoes AW, Rovers MM, Schilder AGM. Effectiviteit
adenotomie of afwachtend beleid bij kinderen met recidiverende bovensteluchtweginfecties. Geen
verschil gevonden in gerandomiseerd onderzoek. Ned Tijdschr Geneeskd 2012;156:A4380.
Boonman-de Winter LJM, Rutten FH, Cramer MJM, Landman MJ, Liem AH, Rutten GEHM, Hoes
AW. High prevalence of previously unknown heart failure and left ventricular dysfunction in patients
with type 2 diabetes. Diabetologia 2012; 55: 2154-62.
Broekhuizen BD, Sachs AP, Hoes AW, Verheij TJ, Moons KG. Diagnostic management of chronic
obstructive pulmonary disease. Neth J Med 2012; 70: 6-11.
Broekhuizen BD, Sachs AP, Verheij TJ, Janssen KJ, Asma G, Lammers JW, Hage R, Lammers E,
Hoes AW, Moons KG. Accuracy of symptoms, signs, and C-reactive protein for early chronic
obstructive pulmonary disease. Br J Gen Pract 2012; 62: e632-8.
Bruins Slot MHE, Rutten FH, Heijden GJMG van der, Doevendans PA, Mast EG, Bredero AC, Glatz
JFC, Hoes AW. Gender differences in pre-hospital time delay and symptom presentation in patients
suspected of acute coronary syndrome in primary care. Fam Pract 2012; 29: 332-7.
Cate-Hoek AJ ten, van der Velde EF, Toll DB, van Weert HC, Moons KG, Büller HR, Hoes AW, Joore
MA, Oudega R, Prins MH, Stoffers HE. Common alternative diagnoses in general practice when deep
venous thrombosis is excluded. Neth J Med 2012;70:130-5.
Geersing GJ, Erkens PM, Lucassen WA, Büller HR, Cate HT, Hoes AW, Moons KG, Prins MH,
Oudega R, van Weert HC, Stoffers HE. Safe exclusion of pulmonary embolism using the Wells rule
and qualitative D-dimer testing in primary care: prospective cohort study. BMJ 2012; 345:e6564. doi:
10.1136/bmj.e6564.
Geersing G-J, Erkens PMG, Lucassen WAM, Büller HR, Ten Cate H, Hoes AW, Moons KGM, Prins
MH, Oudega R, Weert HCPM van, Stoffers HEJH. Safe exclusion of pulmonary embolism using the
Wells rule and qualitative D-dimer testing in Primary care: Prospective cohort study. BMJ (Online)
2012; 345: 7880.
Geersing G-J, Oudega R, Hoes AW, Moons KGM. Managing pulmonary embolism using prognostic
models: Future concepts for primary care. CMAJ 2012; 184: 305-10.
Güder G, Brenner S, Angermann CE, Ertl G, Held M, Sachs AP, Lammers JW, Zanen P, Hoes AW,
Stork S, Rutten FH "GOLD or lower limit of normal definition? A comparison with expert-based
diagnosis of chronic obstructive pulmonary disease in a prospective cohort-study". Respir Res
2012;13:13.
Güder G, Rutten FH, Brenner S, Angermann CE, Berliner D, Ertl G, Jany B, Lammers JW, Hoes AW,
Störk S. The impact of heart failure on the classification of COPD severity. J Card Fail 2012;18(8):63744.
Lip GYH, Ponikowski P, Andreotti F, Anker SD, Filippatos G, Homma S, Morais J, Pullicino P,
Rasmussen LH, Marin F, Lane DA, McMurray J, Hoes A, Ten Berg J, De Caterina R, Kristensen S,
Zeymer U. Thrombo-embolism and antithrombotic therapy for heart failure in sinus rhythm. A joint
consensus document from the ESC Heart Failure Association and the ESC Working Group on
Thrombosis. Eur J Heart Fail 2012; 14: 681-695.
Luttik ML, Brons M, Jaarsma T, Hillege HL, Hoes A, de Jong R, Linssen G, Lok DJ, Berger M, van
Veldhuisen DJ. Design and methodology of the COACH-2 (Comparative study on guideline
adherence and patient compliance in heart failure patients) study: HF clinics versus primary care in
stable patients on optimal therapy. Neth Heart J 2012; 20 (7-8):307-12
McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, Falk V, Filippatos G,
Fonseca C, Sanchez MA, Jaarsma T, Køber L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM,
Popescu BA, Rønnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA,
Zannad F, Zeiher A, Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, FunckBrentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA,
Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, McDonagh T,
Sechtem U, Bonet LA, Avraamides P, Ben Lamin HA, Brignole M, Coca A, Cowburn P, Dargie H,
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Curriculum Vitae
Arno Hoes
Elliott P, Flachskampf FA, Guida GF, Hardman S, Iung B, Merkely B, Mueller C, Nanas JN, Nielsen
OW, Orn S, Parissis JT, Ponikowski P. ESC Guidelines for the diagnosis and treatment of acute and
chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic
Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart
Failure Association (HFA) of the ESC. Eur J Heart Fail 2012; 14(8):803-69
Mourik Y van, Moons KG, Bertens LC, Reitsma JB, Hoes AW, Rutten FH. Triage of frail elderly with
reduced exercise tolerance in primary care (TREE). A clustered randomized diagnostic study. BMC
Public Health 2012; 12: 385.
Oerlemans MIFJ, Mosterd A, Dekker MS, de Vrey EA, van Mil A, Pasterkamp G, Doevendans PA,
Hoes AW, Sluijter JPG. Early assessment of acute coronary syndromes in the emergency
department: The potential diagnostic value of circulating microRNAs. EMBO Molecular Medicine
2012; 4: 1176-85.
Oudejans I, Mosterd A, Zuithoff NP, Hoes AW. Applicability of current diagnostic algorithms in geriatric
patients suspected of new, slow onset heart failure. Age Ageing 2012;41:309-16.
Oudejans I, Mosterd A, Zuithoff NP, Hoes AW. Comorbidity drives mortality in newly diagnosed heart
failure: a study among geriatric outpatients. J Card Fail 2012;18:47-52.
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, Albus C, Benlian P, Boysen G,
Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A,
Prescott E, Ryden L, Scherer M, Syvänne M, Scholte Op Reimer WJ, Vrints C, Wood D, Zamorano
JL, Zannad F, Cooney MT, Bax J, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, FunckBrentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA,
Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, Funck-Brentano
C, Sirnes PA, Aboyans V, Ezquerra EA, Baigent C, Brotons C, Burell G, Ceriello A, De Sutter J,
Deckers J, Del Prato S, Diener HC, Fitzsimons D, Fras Z, Hambrecht R, Jankowski P, Keil U, Kirby M,
Larsen ML, Mancia G, Manolis AJ, McMurray J, Pajak A, Parkhomenko A, Rallidis L, Rigo F, Rocha
E, Ruilope LM, van der Velde E, Vanuzzo D, Viigimaa M, Volpe M, Wiklund O, Wolpert C. European
Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint
Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease
Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts)
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Rehabilitation (EACPR). Eur Heart J 2012 May 3;. [Epub ahead of print]
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren W.M.M, Albus C, Benlian P, Boysen
G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani
A, Prescott E, Ryden L, Scherer M, Syvänne M, Scholte Op Reimer W.J, Vrints C, Wood D,
Zamorano J.L, Zannad F, Cooney M.T, Bax J, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard
R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C,
Popescu B.A, Reiner Ž, Sechtem U, Sirnes P.A, Tendera M, Torbicki A, Vahanian A, Windecker S,
Funck-Brentano C, Sirnes P.A, Aboyans V, Ezquerra E.A, Baigent C, Brotons C, Burell G, Ceriello A,
De Sutter J, Deckers J, Del Prato S, Diener H.C, Fitzsimons D, Fras Z, Hambrecht R, Jankowski P,
Keil U, Kirby M, Larsen M.L, Mancia G, Manolis A.J, McMurray J, Pajak A, Parkhomenko A, Rallidis L,
Rigo F, Rocha E, Ruilope L.M, Van Der Velde E, Vanuzzo D, Viigimaa M, Volpe M, Wiklund O,
Wolpert C. Erratum: 'European Guidelines on cardiovascular disease prevention in clinical practice
(version 2012)' the Fifth Joint Task Force of the European Society of Cardiology and Other Societies
on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine
societies and by invited experts) Eur Heart J 2012;33(17):2126 .
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren WMM, Albus C, Benlian P, Boysen
G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani
A, Prescott E, Ryden L, Scherer M, Syvänne M, Scholte Op Reimer WJM, Vrints C, Wood D,
Zamorano JL, Zannad F. European Guidelines on cardiovascular disease prevention in clinical
practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other
Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of
nine societies and by invited experts). Atherosclerosis 2012; 223: 1-68.
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren WM, Albus C, Benlian P, Boysen G,
Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A,
Prescott E, Ryden L, Scherer M, Syvänne M, Scholte Op Reimer WJ, Vrints C, Wood D, Zamorano
JL, Zannad F. European Guidelines on cardiovascular disease prevention in clinical practice (version
2012). Eur J Prev Cardiol. 2012 Jul 4;. [Epub ahead of print]
Perk J, De Backer G, Gohlke H, Graham I, Reiner Ž, Verschuren M, Albus C, Benlian P, Boysen G,
Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A,
Prescott E, Ryden L, Scherer M, Syvänne M, Scholte Op Reimer WJM, Vrints C, Wood D, Zamorano
JL, Zannad F. Europejskie wytyczne dotyczace
̧ zapobiegania chorobom serca i naczyń w praktyce
klinicznej na 2012 rok. Kardiologia Polska 2012; 70 (Suppl. 1): S1 - S99.
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Curriculum Vitae
Arno Hoes
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, Albus C, Benlian P, Boysen G,
Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A,
Prescott E, Ryden L, Scherer M, Syvänne M, Op Reimer WJMS, Vrints C, Wood D, Zamorano JL,
Zannad F. European guidelines on cardiovascular disease prevention in clinical practice (Version
2012) Revista Espanola de Cardiologia 2012; 65: 937.e1-e66.
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren WMM, Albus C, Benlian P, Boysen
G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani
A, Prescott E, Ryden L, Scherer M, Syvänne M, Op Reimer WJMS, Vrints C, Wood D, Zamorano JL,
Zannad F. European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version
2012) - The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on
Cardiovascular Disease Prevention in Clinical Practice (Constituted by Representatives of Nine
Societies and by Invited Experts). Int J Behav Med 2012; 1 - 86.
Putzeist M, Heemstra HE, Garcia JL, Mantel-Teeuwisse AL, Gispen-De Wied CC, Hoes AW,
Leufkens HGM. Determinants for successful marketing authorisation of orphan medicinal products in
the EU. Drug Discovery Today 2012; 17: 352-8.
Quanjer P, Vaz Fragoso CA, Miller MR, Güder G, Störk S, Hoes AW, Rutten F. GOLD or lower limit of
normal definition? a letter and authors' response. Respir Res 2012; 26;13(1):61.
Roalfe AK, Mant J, Doust JA, Barton P, Cowie MR, Glasziou P, Mant D, McManus RJ, Holder R,
Deeks JJ, Doughty RN, Hoes AW, Fletcher K, Hobbs FDR. Development and initial validation of a
simple clinical decision tool to predict the presence of heart failure in primary care: the MICE (Male,
Infarction, Crepitations, Edema) rule. Eur J Heart Fail 2012; 14:1000-8.
Rutten FH, Heddema WS, Daggelders GJ, Hoes AW. Primary care patients with heart failure in the
last year of their life. Fam Pract 2012; 29: 36-42.
Rutten FH, Hoes AW. Chronic obstructive pulmonary disease: a slowly progressive cardiovascular
disease masked by its pulmonary effects? Eur J Heart Fail 2012; 14: 348-50.
Warnier MJ, Rutten FH, Kors JA, Lammers JWJ, Boer A de, Hoes AW, Bruin ML de. Cardiac
arrhythmias in adult patients with asthma. J Asthma 2012;49:942-6. doi:
10.3109/02770903.2012.724132
Ali MS, Groenwold RH, Pestman WR, Belitser SV, Hoes AW, de Boer A, Klungel OH. Timedependent propensity score and collider-stratification bias: an example of beta2-agonist use and the
risk of coronary heart disease. Eur J Epidemiol. 2013; 28 (4); 291-9.
Backus BE, Six AJ, Kelder JC, Bosschaert MAR, Mast EG, Mosterd A, Veldkamp RF, Wardeh AJ, Tio
R, Braam R, Monnink SHJ, Tooren R van, Mast TP, Akker F van den, Cramer MJM, Poldervaart JM,
Hoes AW, Doevendans PA. A prospective validation of the HEART score for chest pain patients at the
emergency department. Int J Cardiol 2013; 168(3):2153-8.
Bertens LC, Broekhuizen BD, Naaktgeboren CA, Rutten FH, Hoes AW, van Mourik Y, Moons KG,
Reitsma JB. Use of expert panels to define the reference standard in diagnostic research: a
systematic review of published methods and reporting. PLoS Med 2013; 10(10): e1001531.
Bertens LC, Rutten FH, Reitsma JB, Mourik Y van, Broekhuizen BDL, Hoes AW, Moons KGM,
Lammers JWJ. Development and validation of a model to predict the risk of exacerbations in chronic
obstructive pulmonary disease. Int J COPD 2013; 8; 493-9.
Blom MT, Warnier MJ, Bardai A, Berdowski J, Koster RW, Souverein PC, Hoes AW, Rutten FH, de
Boer A, Bruin ML de, Tan HL. Reduced in-hospital survival rates of out-of-hospital cardiac arrest
victims with obstructive pulmonary disease. Resuscitation 2013, 84; 569-74.
Boonacker CWB, Aardweg MTA van den, Broos PH, Hoes AW, Schilder AGM, Rovers MM.
Immediate adenoidectomy vs initial watchful waiting strategy in children with recurrent upper
respiratory tract infections an economic evaluation. JAMA Otolaryngol Head Neck Surg 2013; 139(2):
129 - 33.
Bruins Slot MH, Rutten FH, Heijden GJ van der, Doevendans PA, Mast EG, Bredero AC, van der
Spoel OP, Glatz JF, Hoes AW. Diagnostic value of a heart-type fatty acid-binding protein (H-FABP)
bedside test in suspected acute coronary syndrome in primary care. Int J Cardiol 2013; 168 (2); 14859.
Bruins Slot MH, Heijden GJMG van der, Stelpstra SD, Hoes AW, Rutten FH. Point-of-care tests in
suspected acute myocardial infarction: A systematic review. Int J Cardiol 2013; 168 (6): 5355-62
Duijnhoven RG, Straus SMJM, Raine JM, Boer A de, Hoes AW, Bruin ML de. Number of patients
studied prior to approval of new medicines: A database analysis. PLoS Med 2013; 10(3); e1001407
Groenwold RHH, Hoes AW, Vandenbroucke JP. Patiënt-controleonderzoek: het belang van de juiste
controlepersonen. Ned Tijdschr Geneeskd 2013;157:A5697.
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Curriculum Vitae
Arno Hoes
Groenwold RH, Klungel OH, Altman DG, Graaf Y van der, Hoes AW, Moons KG; PROTECT WP2
(Pharmacoepidemiological Research on Outcomes of Therapeutics by a European Consortium, Work
Programme 2 [Framework for pharmacoepidemiology studies]). Adjustment for continuous
confounders: an example of how to prevent residual confounding. CMAJ 2013; 185(5): 401-6. doi:
10.1503/cmaj.120592.
Hoes AW. Should we screen for heart failure in the elderly? Eur J Heart Fail. 2013; 15 (2): 125-7. doi:
10.1093/eurjhf/hfs213
Hoog VC de, Timmers L, Schoneveld AH, Wang JW, Weg SM van de, Sze SK, Keulen JK van, Hoes
AW, Ruijter HM den, Kleijn DP de, Mosterd A. Serum extracellular vesicle protein levels are
associated with acute coronary syndrome. Europ Heart J Acute Cardiovasc Care 2013; 2(1): 53-60.
Johansson P, Lesman-Leegte I, Lundgren J, Hillege HL, Hoes A, Sanderman R, Veldhuisen DJ van,
Jaarsma T. Time-course of depressive symptoms in patients with heart failure. J Psychosomatic Res
2013; 74: 238-43.
Kelder H, Cramer MJ, Wijngaarden J van, Tooren R van, Mosterd A, Moons C, Lammers JW, Cowie
M, Grobbee R, Hoes A. Lichamelijk onderzoek en aanvullende tests bij hartfalen. Huisarts Wet 2013;
56 (3): 110-12.
Montalescot G, Sechtem U, Achenbach S, Andreotti F, Arden C, Budaj A, Bugiardini R, Crea F,
Cuisset T, Di Mario C, Ferreira J.R, Gersh B.J, Gitt A.K, Hulot J.-S, Marx N, Opie L.H, Pfisterer M,
Prescott E, Ruschitzka F, Sabaté M, Senior R, Taggart D.P, Van Der Wall E.E, Vrints C.J.M, Zamorano
J.L, Baumgartner H, Bax J.J, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D,
Hoes A.W, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli M.F,
Ponikowski P, Sirnes P.A, Tamargo J.L, Tendera M, Torbicki A, Wijns W, Windecker S, Valgimigli M,
Claeys M.J, Donner-Banzhoff N, Frank H, Funck-Brentano C, Gaemperli O, Gonzalez-Juanatey J.R,
Hamilos M, Husted S, James S.K, Kervinen K, Kristensen S.D, Maggioni A.P, Romeo F, Rydén L,
Simoons M.L, Steg P.G, Timmis A, Yildirir A. 2013 ESC guidelines on the management of stable
coronary artery disease. Eur Heart J 2013; 34 (38): 2949 - 3003.
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren WM, Albus C, Benlian P, Boysen G,
Cifkova R, Deaton C, Ebrahim S, Fisher M, Germanò G, Hobbs R, Hoes A, Karadeniz S, Mezzani A,
Prescott E, Ryden L, Scherer M, Syvanne M, Scholte Op Reimer WJ, Vrints C, Wood D, Zamorano
JL, Zannad F. [European guidelines on cardiovascular disease prevention in clinical practice (version
2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on
Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine
societies and by invited experts)]. G Ital Cardiol (Rome) 2013;14(5):328-92. Italian.
Poldervaart JM, Reitsma JB, Koffijberg H, Backus BE, Six AJ, Doevendans PA, Hoes AW. The impact
of the HEART risk score in the early assessment of patients with acute chest pain: design of a
stepped wedge, cluster randomised trial. BMC Cardiovasc Disord 2013 Sep 26;13(1):77. [Epub
ahead of print]
Putzeist M, Mantel-Teeuwisse AK, Llinares J, Gispen-De Wied CC, Hoes AW, Leufkens HGM. EU
marketing authorisation review of orphan and non-orphan drugs does not differ. Drug Disc Today
2013; 18 (19-20) pp. 1001-6 .
Putzeist M, Mantel-Teeuwisse AK, Wied CC, Hoes AW, Leufkens HGM, Vrueh RLA de. Drug
development for exceptionally rare metabolic diseases: challenging but not impossible. Orphanet J
Rare Dis 2013; 8(1): 179. [Epub ahead of print]
Rutten FH, Groenwold RHH, Sachs APE, Grobbee DE, Hoes AW. B-blockers and all-cause mortality
in adults with episodes of acute bronchitis: an observational study. PLoS ONE 2013; 8(6): e67122.
doi:10.1371/journal.pone.0067122
Rutten F, Heddema W, Daggelders G, Hoes A. Het laatste jaar van patiënten met hartfalen. Huisarts
Wet 2013; 56(1):18-21.
Rydén L, Grant PJ, Anker SD, Berne C, Cosentino F, Danchin N, Deaton C, Escaned J, Hammes HP, Huikuri H, Marre M, Marx N, Mellbin L, Ostergren J, Patrono C, Seferovic P, Uva MS, Taskinen MR, Tendera M, Tuomilehto J, Valensi P, Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno
H, Dean V, Erol Ç, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P, Knuuti J, Kolh P, Lancellotti P,
Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL, Torbicki A, Wijns W,
Windecker S, De Backer G, Ezquerra EA, Avogaro A, Badimon L, Baranova E, Betteridge J, Ceriello
A, Funck-Brentano C, Gulba DC, Kjekshus JK, Lev E, Mueller C, Neyses L, Nilsson PM, Perk J,
Reiner Ž, Sattar N, Schächinger V, Scheen A, Schirmer H, Strömberg A, Sudzhaeva S, Viigimaa M,
Vlachopoulos C, Xuereb RG. ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases
developed in collaboration with the EASD. Eur Heart J 2013; 34 (39): 3035 - 87 .
Schmidt AF, Nielen M, Klungel OH, Hoes AW, Boer A de, Groenwold RHH, Kirpensteijn J, Amsellem
P, Bacon N, Berg J, Kow K, Kurzman I, Maritato K, Moore A, Morello E, Sottnik J, Vail D. Prognostic
29/1/15
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Curriculum Vitae
Arno Hoes
factors of early metastasis and mortality in dogs with appendicular osteosarcoma after receiving
surgery: An individual patient data meta-analysis. Prev Veterinary Med 2013; 112 (3-4): 414-22.
Schmidt AF, Rovers MM, Klungel OH, Hoes AW, Knol MJ, Nielen M, Boer A de, Groenwold RH.
Differences in interaction and subgroup-specific effects were observed between randomized and
nonrandomized studies in three empirical examples. J Clin Epidemiol 2013: 66 (6); 599-607.
Trappenburg JCA, Jonkman NH, Jaarsma T, Os-Medendorp H van, Kort H, Wit NJ de, Hoes AW,
Schuurmans MJ. Self-management: one size does not fit all. [letter] Patient Educ Couns 2013; 92 (1):
134-7.
Veldhuisen DJ van, Linssen GC, Jaarsma T, Gilst WH van, Hoes AW, Tijssen JG, Paulus WJ, Voors
AA, Hillege HL. Brain Natriuretic Peptide and Prognosis in Heart Failure Patients with Preserved and
Reduced Ejection Fraction. J Am Coll Cardiol 2013; S0735-1097 (13)00484-1. doi:
10.1016/j.jacc.2012.12.044. [Epub ahead of print]
Veldhuisen DJ van, Linssen GCM, Jaarsma T, Gilst WH van, Hoes AW, Tijssen JGP, Paulus WJ,
Voors AA, Hillege HL. B-type natriuretic peptide and prognosis in heart failure patients with preserved
and reduced ejection fraction. J Am Coll Cardiol 2013; 61: 1498-1506.
Wangge G, Boer A de, Klungel OH, Hoes AW, Knol MJ. Expert-opinion on non-inferiority margin: A
case study of oral anti-coagulant agents for prophylaxis of venous thromboembolic events after
orthopedic surgery. Thromb Res 2013; 131 (4): 368-71.
Wangge G, Klungel OH, Roes KC, Boer A de, Hoes AW, Knol MJ. Should non-inferiority drug trials be
banned altogether? Drug Discov Today. 2013 Jan 14;. [Epub ahead of print]
Wangge G, Putzeist M, Knol MJ, Klungel OH, Gispen-De Wied CC, de Boer A, Hoes AW, Leufkens
HG, Mantel-Teeuwisse AK. Regulatory scientific advice on non-inferiority drug trials. PLoS ONE 2013;
8(9): e74818.
Wangge G, Roes KC, de Boer A, Hoes AW, Knol MJ. The challenges of determining noninferiority
margins: a case study of noninferiority randomized controlled trials of novel oral anticoagulants. CMAJ
2013;185: 222-7. doi: 10.1503/cmaj.120142.
Warnier MJ, Blom MT, Bardai A, Berdowksi J, Souverein PC, Hoes AW, Rutten FH, Boer A de, Koster
RW, Bruin ML de, Tan HL. Increased risk of sudden cardiac arrest in obstructive pulmonary disease: a
case-control study. PLoS One. 2013;8(6):e65638.
Warnier MJ, Rutten FH, Numans ME, Kors JA, Tan HL, de Boer A, Hoes AW, De Bruin ML.
Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease. COPD
2013;10(1):62-71.
Ali MS, Groenwold RH, Pestman WR, Belitser SV, Roes KC, Hoes AW, de Boer A, Klungel OH.
Propensity score balance measures in pharmacoepidemiology: a simulation study.
Pharmacoepidemiol Drug Saf 2014; 23 (8): 802-11.
Ali MS, Uddin MJ, Groenwold RH, Pestman WR, Belitser SV, Hoes AW, de Boer A, Roes KC, Klungel
OH. Quantitative falsification of instrumental variables assumption using balance measures.
Epidemiology 2014; 25(5): 770-2.
Bertens LCM, Reitsma JB, Mourik Y van, Lammers J-WJ, Moons KGM, Hoes A., Rutten FH. COPD
detected with screening: Impact on patient management and prognosis. Eur Resp J 2014; 44 (6):
1571-8 .
Boonacker CW, Rovers MM, Browning GG, Hoes AW, Schilder AG, Burton MJ. Adenoidectomy with
or without grommets for children with otitis media: an individual patient data meta-analysis. Health
Technol Assess 2014;18(5):1-118.
Boonman-de Winter LJM, Rutten FH, Cramer MJ, Landman MJ, Zuithoff NPA, Liem AH, Hoes AW.
Efficiently screening heart failure in patients with type 2 diabetes.
Bruins Slot MH, Rutten FH, Heijden GJ van der, Doevendans PA, Mast EG, Bredero AC, Spoel OP
van der, Glatz JF, Hoes AW. De H-FABP-sneltest bij verdenking op acuut coronair syndroom. Huisarts
Wet 2014; 57(7): 338-41.
Duijnhoven RG, Straus SMJM, Souverein PC, Boer A de, Bosch JLHR, Hoes AW, Bruin, ML de.
Long-term use of 5α-reductase inhibitors and the risk of male breast cancer. Cancer Causes Contr
2014; 25 (11): 1577-82.
Erbel R, Aboyans V, Boileau C, Bossone E, Di Bartolomeo R, Eggebrecht H, Evangelista A, Falk V,
Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung, B, Manolis AJ, Meijboom F, Nienaber CA,
Roffi M, Rousseau H, Sechtem U, Sirnes PA, Von Allmen RS, Vrints CJM, Zamorano JL, Achenbach
S, Baumgartner, H, Bax, JJ, Bueno, H, Dean V, Deaton C, Erol Ç, Fagard R, Ferrari R, Hasdai D,
Hoes A, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF,
Ponikowski P, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Czern M, Deanfield J, Mario
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Curriculum Vitae
Arno Hoes
C di, Pepi M, Taboada MJS, Sambeek MR van, Vlachopoulos C. 2014 ESC guidelines on the
diagnosis and treatment of aortic diseases 2014; Eur Heart J 2014; 35 (41): 2873-2926.
Geersing GJ, Zuithoff NPA, Kearon C, Anderson DR, Cate-Hoek AJ ten, Elf JL, Bates SM, Hoes AW,
Kraaijenhagen RA, Oudega R, Schutgens REG, Stevens SM, Woller SC, Wells PS, Moons KGM.
Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual
patient data meta-analysis. BMJ 2014;348:g1340
Grobbee DE, Hoes AW. Clinical Epidemiology. Principles, methods, and applications for clinical
research. 2nd ed. Boston: Jones and Bartlett Publishers, 2015. ISBN 978-1-4496-7432-8 / 1-44967432-1.
Groenwold RH, Tilling K, Moons KG, Hoes AW, Ent CK van der, Kramer MS, Martin RM, Sterne JA.
Breast-feeding and health consequences in early childhood: is there an impact of time-dependent
confounding? Ann Nutr Metab 2014;65(2-3):139-48.
Güder G, Brenner S, Störk S, Hoes A, Rutten FH. Chronic obstructive pulmonary disease in heart
failure: Accurate diagnosis and treatment. Eur J Heart Failure 2014; 16 (12): 1273-82.
Jennings C, Kotseva K, DeBacquer D, Hoes A, Velasco J de, Brusaferro S, Mead A, Jones J, Tonstad
S, Wood D, on behalf of EUROACTION PLUS Study Group. Effectiveness of a preventive cardiology
programme for high CVD risk persistent smokers: the EUROACTION PLUS varenicline trial.
European Heart Journal 2014; 35 (21); 1411-20.
Jonkman NH, Westland H, Trappenburg JC, Groenwold RH, Effing-Tijdhof TW, Troosters T, Palen J
van der, Bourbeau J, Jaarsma T, Hoes AW, Schuurmans MJ. Towards tailoring of self-management
for patients with chronic heart failure or chronic obstructive pulmonary disease: a protocol for an
individual patient data meta-analysis. BMJ Open. 2014 May 23;4(5):e005220. doi: 10.1136/bmjopen2014-005220.
Karyanti MR, Uiterwaal CS, Kusriastuti R, Hadinegoro SR, Rovers MM, Heesterbeek H, Hoes AW,
Bruijning-Verhagen P. The changing incidence of Dengue Haemorrhagic Fever in Indonesia: a 45year registry-based analysis. BMC Infect Dis 2014; 14(1):412. doi: 10.1186/1471-2334-14-412.
Kristensen SD, Knuuti J, Saraste A, Anker S, Bøtker HE, De Hert S, Ford I, Gonzalez-Juanatey JR,
Gorenek B, Heyndrickx GR, Hoeft A, Huber K, Iung B, Kjeldsen KP, Lüscher TF, Pierard L, Pocock S,
Price S, Roffi M, Sirnes PA, Sousa-Uva M, Voudris V, Funck-Brentano C, Zamorano JL, Achenbach
S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol C, Fagard R, Ferrari R, Hasdai D, Hoes
AW, Kirchhof P, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P,
Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S, Solca M, Brichant J-F, De Robertis E,
Longrois D, Langenecker SK, Wichelewski J. 2014 ESC/ESA Guidelines on non-cardiac surgery:
Cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery:
Cardiovascular assessment and management of the European Society of Cardiology (ESC) and the
European Society of Anaesthesiology (ESA). Eur Heart J 2014; 35 (35): 2383 - 2431.
Luttik MLA, Jaarsma T, Geel PP van, Brons M, Hillege HL, Hoes AW, Jong R de, Linssen G, Lok DJA,
Berge M, Veldhuisen DJ van. Long-term follow-up in optimally treated and stable heart failure patients:
Primary care vs. heart failure clinic. Results of the COACH-2 study. Eur J Heart Fail 2014; 16
(11):1241-8.
Mourik Y van, Bertens LC, Cramer MJ, Lammers JW, Reitsma JB, Moons KG, Hoes AW, Rutten FH.
Unrecognized heart failure and chronic obstructive pulmonary disease (COPD) in frail elderly detected
through a near-home targeted screening strategy. J Am Board Fam Med 2014; 27(6): 811-21. doi:
10.3122/jabfm.2014.06.140045.
Mourik Y van, Rutten FH, Moons KG, Bertens LC, Hoes AW, Reitsma JB. Prevalence and underlying
causes of dyspnoea in older people: a systematic review. Age Ageing 2014; 0: 1-8.
Riet EE van, Hoes AW, Limburg A, Hoeven H van der, Landman MA, Rutten FH. Strategy to
recognize and initiate treatment of chronic heart failure in primary care (STRETCH): a cluster
randomized trial. BMC Cardiovasc Disord 2014;14(1):1.
Schmidt AF, Groenwold RHH, Delden JJ van, Does Y van der, Klungel OH, Roes KCB, Hoes AW,
Graaf R van der. Justification of exclusion criteria was underreported in a review of cardiovascular
trials. J Clin Epidemiol 2014; 67 (6): 635 - 44.
Schmidt AF, Groenwold RHH, Knol MJ, Hoes AW, Nielen M, Roes KCB, Boer A de, Klungel OH.
Exploring interaction effects in small samples increases rates of false-positive and false-negative
findings: results from a systematic review and simulation study. J Clin Epidemiol. 2014; 67 (7): 821-9 .
Schmidt AF, Hoes AW, Groenwold RHH. Comments on: Taylor R. et al. 'The use of propensity scores
and observational data to estimate randomized controlled trial generalizability bias. Stat Med 2013'.
Stat Med 2014; 33: 536-7.
Trappenburg J, Jonkman N, Jaarsma T, Os-Medendorp H van, Kort H, Wit N de, Hoes A,
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Curriculum Vitae
Arno Hoes
Schuurmans M. Zelfmanagement bij chronische ziekten. Huisarts Wet 2014;57(3):120-4.
Uddin MJ, Groenwold RHH, Boer A de, Belitser SV, Roes KCB, Hoes AW, Klungel OH. Performance
of instrumental variable methods in cohort and nested case-control studies: A simulation study.
Pharmacoepidemiol Drug Saf 2014; 23 (2); 165-77.
Venekamp RP, Rovers MM, Hoes AW, Knol MJ. Subgroup analysis in randomized controlled trials
appeared to be dependent on whether relative or absolute effect measures were used. J Clin
Epidemiol 2014; 67 (4): 410-5.
Wang X, Yang F, Bots ML, Guo W, Zhao D, Hoes AW, Vaartjes I. Prevalence and clustering of
cardiovascular risk factors in adults in Northeast China. Heart Asia 2014; 6 (1): 122-7.
Warnier MJ, Holtkamp FA, Rutten FH, Hoes AW, Boer A de, Mol PG, Bruin ML de. Quality of drug
label information on QT interval prolongation. Int J Risk Saf Med 2014;26(2):89-98.
Warnier MJ, Holtkamp FA, Rutten FH, Hoes AW, Boer A de, Mol PG, Bruin ML de. Safety information
on QT-interval prolongation: comparison of European Union and United States drug labeling. Drug
Discov Today. 2014 Sep;19(9):1294-7. doi: 10.1016/j.drudis.2014.06.017.
Warnier MJ, Rutten FH, Boer A de, Hoes AW, Bruin ML de. Resting heart rate is a risk factor for
mortality in chronic obstructive pulmonary disease, but not for exacerbations or pneumonia. PLoS
One 2014; 9(8): e105152.
Windecker S, Kolh P, Alfonso F, Collet J-P, Cremer J, Falk V, Filippatos G, Hamm C, Head SJ, Jüni P,
Kappetein AP, Kastrati A, Knuuti J, Landmesser U, Laufer G, Neumann F-J, Richter DJ, Schauerte P,
Uva MS, Stefanini GG, Taggart DP, Torracca L, Valgimigli M, Wijns W, Witkowski A, Baumgartner H,
Bax JJ, Bueno H, Dean V, Deaton C, Erol Ç, Fagard R, Ferrari R, Hasdai D, Hoes AW, Kirchhof P,
Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Sirnes PA, Tamargo JL,
Tendera M, Torbicki A, Achenbach S, Pepper J, Anyanwu A, Badimon L, Bauersachs J, Baumbach A,
Beygui F, Bonaros N, De Carlo M, Dobrev D, Dunning J, Eeckhout E, Gielen S, Luckraz H, Mahrholdt
H, Montalescot G, Paparella D, Rastan AJ, Sanmartin M, Sergeant P, Silbe SR, Tamrgo J, Ten Berg J,
Thiele H, Van Geuns R-J, Wagner H-O, Wassmann S, Wendler O, Zamorano JL. 2014 ESC/EACTS
Guidelines on myocardial revascularization. Eur Heart J 2014; 35 (37); 2541-2619.
Ali MS, Groenwold RHH, Belitser SV, Pestman WR, Hoes AW, Roes KCB, Boer AD, Klungel OH.
Reporting of covariate selection and balance assessment in propensity score analysis is suboptimal: A
systematic review. J Clin Epidemiol 2015; 68 (2); 122 – 31.
Hoes AW. Optimaliseren van bloeddrukbehandeling. Kan de patiënt het zelf beter? Ned Tijdschr
Geneeskd 2015;159: A8498
Projects
Memberships
Professor Hoes is involved in multiple projects (>50)
Member, Editorial Board European Journal of Heart Failure.
Member, CBO Dutch National Guideline Committee on Cardiovascular Risk Management.
Member, Scientific Committee, Medicines Evaluation Board.
Programme director, Clinical Epidemiology MSc Training Programme, UMC Utrecht
Member, European Task Force for Cardiovascular Risk Management
Chair, CBO Task Force, Heart Failure guidelines, the Netherlands
Member, Scientific Advisory Council, Netherlands Heart Foundation
Chair, Dekker Stipendium, Netherlands Heart Foundation
Member, Health Council, the Netherlands
Board Member, Heart Failure Association, European Society of Cardiology
Member, Committee for Practice Guidelines (GPG) , European Society of Cardiology
Member, Patient Care Committee, Heart Failure Association, European Society of Cardiology
Fellow, European Society of Cardiology (FESC)
Editorial Board Member International Journal of Cardiology
Other Relevant Information
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