haematologica Journal of the European Hematology Association Published by the Ferrata Storti Foundation Table of Contents Volume 100, Issue 2: February 2015 Cover Figure Artistic view on the structure of Factor VIII. (image created by www.somersault1824.com) Editorials 143 Tumor-associated macrophages in diffuse large B-cell lymphoma Robert Kridel, et al. 145 Inherited thrombocytopenias in the era of personalized medicine Patrizia Noris, et al. Review Article 149 Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicity Johannes Oldenburg, et al. Articles Hematopoiesis 157 In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis Stijn Vanhee, et al. Iron Metabolism & its Disorders 167 A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis Patrick Gutschow, et al. Red Cell Biology & its Disorders 178 Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion Mario Falchi, et al. Coagulation & its Disorders 188 Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism Tom van der Hulle, et al. Myelodysplastic Syndromes 194 Down-regulation of Dicer1 promotes cellular senescence and decreases the differentiation and stem cell-supporting capacities of mesenchymal stromal cells in patients with myelodysplastic syndrome Youshan Zhao, et al. 205 Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group Friederike Braulke, et al. Haematologica 2015; vol. 100 no. 2 - February 2015 http://www.haematologica.org/ haematologica Journal of the European Hematology Association Published by the Ferrata Storti Foundation Acute Myeloid Leukemia 214 Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol Niccolò Bolli, et al. 223 In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent Fanny Angelot-Delettre, et al. 231 A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia Jeffrey E. Lancet, et al. Non-Hodgkin Lymphoma 238 Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial Sari Riihijärvi, et al. 246 The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection Luca Arcaini, et al. Chronic Lymphocytic Leukemia 253 Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia Stefania Fiorcari, et al. Plasma Cell Disorders 263 Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide Inger S. Nijhof, et al. Stem Cell Transplantation 269 Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial Didier Blaise, et al. 275 Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease Isabelle Laverdière, et al. Complications in Hematology 284 Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM 2010-a multicenter study) Morena Caira, et al. Letters to the Editor Letters are available online only at www.haematologica.org/content/100/2.toc e42 IL-1β-releasing human acute myeloid leukemia blasts modulate natural killer cell differentiation from CD34+ precursors Chiara Vitale, et al. http://www.haematologica.org/content/100/2/e42 e46 JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms Shuichi Shirane, et al. http://www.haematologica.org/content/100/2/e46 e49 Pharmacological targeting of β-catenin in normal karyotype acute myeloid leukemia blasts Elizabeth A. Griffiths, et al. http://www.haematologica.org/content/100/2/e49 Haematologica 2015; vol. 100 no. 2 - February 2015 http://www.haematologica.org/ haematologica Journal of the European Hematology Association Published by the Ferrata Storti Foundation e53 The prognostic value of multiparameter flow cytometry minimal residual disease assessment in relapsed multiple myeloma Bruno Paiva, et al. http://www.haematologica.org/content/100/2/e53 e56 Phase II study of bendamustine, bortezomib and dexamethasone as second-line treatment for elderly patients with multiple myeloma: the Intergroupe Francophone du Myelome 2009-01 trial Philippe Rodon, et al. http://www.haematologica.org/content/100/2/e56 e60 A rare case of IGH/MYC and IGH/BCL2 double hit primary plasma cell leukemia Anna Kalff, et al. http://www.haematologica.org/content/100/2/e60 e63 Health-related quality of life from the MM-003 trial of pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed and/or refractory multiple myeloma Kevin W. Song, et al. http://www.haematologica.org/content/100/2/e63 e68 Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation Claire Mayeur, et al. http://www.haematologica.org/content/100/2/e68 e72 Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency Polina Stepensky, et al. http://www.haematologica.org/content/100/2/e72 Haematologica 2015; vol. 100 no. 2 - February 2015 http://www.haematologica.org/
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