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Sevilla · 21 - 23 october 2015
15 ASEICA
INTERNATIONAL
CONGRESS
th
Spanish Society for Cancer Research
Hotel NH Collection Sevilla. Avda Diego Mar tinez Barrio, 8, 41013 Sevilla
Organizing Committee
President
Dr. Pedro Lazo-Zbikowski
Dr. Carlos Camps
Dr. Noemí Reguart
Dr. Gabriel Capellá
Dr. Montserrat Sánchez Cespedes
Dr. Luis Paz-Ares
Dr. Ana Osorio
Dr. Arkaitz Carracedo
Dr. Jesús Paramio
Dr. José Palacios
Scientific Committee
Dr. Pedro Lazo-Zbikowski
Dr. Carlos Camps
Dr. Gabriel Capellà
Dr. Arkaitz Carracedo
Dr. Leonor David
Dr. Antonio García de Herreros
Dr. Alberto Muñoz
Dr. Ana Osorio
Dr. José Palacios
Dr. Jesús Paramio
Dr. Luis Paz-Ares
Dr. Héctor Peinado
Dr. Noemí Reguart
Dr. Montse Sánchez-Céspedes
Dr. Joan Seoane
Dr.Violeta Serra
Dr. George Thomas
Dr. Guillermo Velasco
15th ASEICA
INTERNATIONAL
CONGRESS
Wednesday 21st october
15.00 - 15.05
Meeting opening
15.05 - 15.45
Opening conference. ASEICA Lecture
Targetting telomeres in cancer
Dr. María A. Blasco, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid
15.45 - 17.15
A. Sustaining proliferative signaling & evading growth suppressors
Chairpersons Dr. Jesús Paramio and Dr. Violeta Serra
15.45 - 16.10
Linking senescence and inflammation: the senescence-associated
secretory phenotype (SASP)
Dr. Jesús Gil, MRC Clinical Science Center, Kings College, London, UK
16.10-16.35
Targeting PI3K in breast cancer
Dr. Violeta Serra, Hospital Universitari Vall d’Hebrón (VHIO), Barcelona
16.35-17.00
Tyrosine kinase inhibitors: from “Lazarians responses” to the emergence
of resistance. A focus in lung cancer
Dr. Luis Paz-Ares, Hospital Universitario 12 de Octubre, Madrid
17.00 - 17.15
Selected short talks from presented abstracts
Determination of the proto-oncogenic role of pim1/pim2 kinases in male
reproductive system tumors by using conditional transgenic murine models
Manuel Pedro Jiménez García, Instituto de Biomedicina de Sevilla (IBIS)
15th ASEICA
INTERNATIONAL
CONGRESS
A syntethic lethal screen identifies usp39 as an essential gene for krasdependent cancers
Julia Martínez Fraile, Universidad de Oviedo
17.15 - 17.45
Coffee break and poster viewing
17.45 - 19.15
B. Cancer genomics and tumor heterogeneity
Chairpersons Dr. Montse Sánchez-Céspedes and Dr. José Palacios
17.45 - 18.10
Novel gene alterations and biological networks in lung cancer development
Dr. Montse Sánchez-Céspedes, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona
18.10 - 18.35
Genomic characterization of the role of intratumor heterogeneity in
cancer progression and metastasis
Dr. Ignacio Varela, Instituto de Biomedicina y Biotecnología de Cantabria
(IBBTEC - UC - CSIC - SODERCAN), Santander
18.35 - 19.00
Clinical implications of intrinsic breast cancer subtypes
Dr. Aleix Prat, Hospital Universitari Clínic, Barcelona
19.00 - 19.15
Selected short talks from presented abstracts
Identification of markers of endometrial cancer in exosome-like vesicles
of uterine fluids using a super silac quantitative proteomics approach
Eva Colas, IRB Lleida
Yes1 kinase is a new therapeutic target in non-small cell lung cancer
Irati Garmendia, Centro de Investigación Médica Aplicada, Pamplona
19.15 - 20.30
Round table: clinical applications of genomics
Chairperson Dr. Luis Paz-Ares
Clonal evolution and drug resistance: from cancer avatars to liquid biopsies
Dr. Manuel Hidalgo, Centro de Investigaciones Oncológicas (CNIO), Madrid
Discussants:
Dr. Manuel Hidalgo, Centro de Investigaciones Oncológicas (CNIO), Madrid
Dr. Joan Albanell, Hospital del Mar-Parc de Salut Mar, Barcelona
Dr. Alfonso Berrocal, Hospital General Universitario, Valencia
Thursday 22nd october
08.30 - 10.00
C. Metabolism. Deregulating cellular energetics
Chairpersons Dr. George Thomas and Dr. Arkaitz Carracedo
08.30 - 08.55
Ribosome biogenesis mediates a novel intrinsic p53 checkpoint in cancer
progression
Dr. George Thomas, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona
08.55 - 09.20
Metabolic Dysfunctions in Liver Cancer
Dr. Nabil Djouder, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid
09.20 - 09.45
Metabolic alterations as biomarkers of efficacy in anticancer therapies
targeting the PI3K/AKT/mTOR pathway
Dr. Jordi Rodón, Hospital Universitari Vall d’Hebrón (VHIO), Barcelona
15th ASEICA
INTERNATIONAL
CONGRESS
09.45 - 10.10
Metabolic reprogramming as an escape mechanism against treatment
with multi-tyrosine kinase inhibitors
Dr. Miguel Quintela, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid
10.10 - 10.25
Selected short talks from presented abstracts
Transcriptional regulation of prostate cancer metabolism
Verónica Torrano Moya, CICbioGUNE, Vizcaya
Tanyrase inhibition blocks wnt/β-catenin pathway and reverts resistance
to pi3k and akt inhibitors in colorectal cancer treatment
Oriol Arqués, VHIO, Barcelona
10.25 - 11.00
Coffee break and poster viewing
11.00 - 12.30
D. Resisting cell death
Chairpersons Dr. Guillermo Velasco and Dr. Gabriel Capellà
11.00 - 11.25
Signaling mechanisms involved in the regulation of autophagy-mediated
cancer cell death
Dr. Guillermo Velasco, Universidad Complutense de Madrid, Instituto de Investigaciones
Santarias San Carlos, Madrid
11.25 - 11.50
The two faces of mesenchymal stem cells in myeloid neoplasias
Dr. Simón Méndez-Ferrer, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid
11.50 - 12.15
Cell death induced by inhibition of glucose metabolism
Dr. Cristina Muñoz-Pinedo, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona
12.15 - 12.30
Selected short talks from presented abstracts
Fadd phosphorylation is altered in t-cell lymphoblastic lymphoma.
José Luis Marin Rubio, CBMSO (UAM/CSIC), Madrid
Increased expression of gasdermin-b (gsdmb) associates with resistance
to anti-her2 therapies in her2+ breast cancer
David Sarrió, Universidad Autonóma de Madrid, Madrid
12.30 - 14.00
SATELLITE SYMPOSIUM
Immunology; a new opportunity on cancer
Sponsorized by
Chairperson Dr. Luis Paz-Ares, Hospital Universitario 12 de Octubre, Madrid
Dr. Carlos Camps, Hospital General Universitario de Valencia
12.30 - 12.35
Bienvenida
12.35 - 13.00
Systematization, hierarchies and dependencies on immune system.
Immune checkpoint inhibitors: Clinical results and future
Dr. Alfonso Berrocal, Hospital General Universitario, Valencia
13.00 - 13.15
Immunoscores in cancer: a possible goal to achieve?
Dr. Ignacio Duran, Hospital Virgen del Rocío, Sevilla
13.15 - 13.30
How recent advances in immunotherapy are changing the standard of
care for patients with metastatic melanoma
Dr. Luis de la Cruz, Hospital Universitario Virgen Macarena, Sevilla
13.30 - 13.45
Immunotherapy for lung cancer: recent advances, lessons learned, and
areas for further research
Dr. Luis Paz-Ares, Hospital Universitario 12 de Octubre, Madrid
13.45 - 14.00
Open discussion
15th ASEICA
INTERNATIONAL
CONGRESS
13.30 - 14.30
Lunch
14.00 - 16.00
Poster session with presenters
(odd numbers from 14.00 to 15.00h, even numbers from 15.00 to 16.00h)
16.00 - 17.30
E. Activating invasion & metastasis
Chairpersons Dr. Antonio García de Herreros and Dr. Noemí Reguart
16.00 - 16.25
Snail1, epithelial to mesenchymal transition and fibroblast activation
Dr. Antonio García de Herreros, Universidad Pompeu Fabra (UPF), Barcelona
16.25 - 16.50
Microenviromental regulation of disseminated tumour cells dormancy
Dr. Paloma Bragado, Institut d’Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona
16.50 - 17.15
Regulation of the histone demethylase LSP1 complex: implications in EMT
Dr. José C. Reyes, CABIMER, CSIC-US, Sevilla
17.15 - 17.30
Selected short talks from presented abstracts
Molecular mechanisms involved in peritoneal carcinomatosis of ovarian
cancer
Ricardo Coelho, IPATIMUP, Porto, Portugal
Initiating metastatic disease in the brain: a hostile soil with key resources.
Manuel Valiente, CNIO, Madrid
17.30 - 18.00
Coffee break and poster viewing
18.00 - 19.30
F. Tumor niche and microenvironment
Chairpersons Dr. Héctor Peinado and Dr. Joan Seoane
18.00 - 18.20
Defining the role of tumor secreted exosomes during premetastatic
niche formation
Dr. Héctor Peinado, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid
18.20 - 18.40
Nuevos sensores de microambiente como genes supresores
Dr. Amancio Carnero, Campus Hospital Universitario Virgen del Rocío (IBIS), Sevilla
18.40 - 19.00
The TGF-beta pathway as a therapeutic target against cancer
Dr. Joan Seoane, Hospital Universitari Vall d’Hebrón (VHIO), Barcelona
19.00 - 19.15
Selected short talks from presented abstracts
M-trap: exosome-based capture of tumor cells as a new technology in
peritoneal metastasis
Rafael López, Complejo Hospitalario Univ. De Santiago de Compostela
In vivo loxl2 functions in breast tumor metastasis revealed by gain-andloss-of-function mice models
Alberto Martin, Universidad Autonóma, Madrid
19.20 - 19.40
ASPIC Lecture
Chairperson Dra. Leonor David
The biology and functional contribution of exosomes in cancer
progression and metastasis
Dr. Sonia Melo, MD Anderson Cancer Center, USA and IPATIMUB-Univ. of Porto, Portugal
15th ASEICA
INTERNATIONAL
CONGRESS
Friday 23rd october
09.00 - 10.45
G. Nuclear receptors, transcription and cancer
Chairpersons Dr. Alberto Muñoz and Dr. Ana Osorio
09.00 - 09.20
Targeting nuclear receptors: why we need new combinatorial therapies
for breast cancer
Dr. María del Mar Vivanco, CIC bioGUNE, Vizcaya
09.20 - 09.40
Role of the transcriptional repressor HDAC7 in leukemia and lymphoma
Dr. Maribel Parra, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona
09.40 - 10.05
Vitamin D,VDR and colon cancer
Dr. Alberto Muñoz, Instituto de Investigaciones Biomédicas, CSIC-UAM, Madrid
10.05 - 10.20
Selected short talks from presented abstracts
Genetic inflammation caused by nr5a2 heterozygosity is mediated by
ap-1 and contributes to pancreatitis and pancreatic cancer
Isidoro Cobo, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid
Pushing myc inhibition towards the clinic by direct delivery of cell-
penetrating peptides
Marie Eve Beaulieu, Vall d’Hebrón, Institute of Oncology, Barcelona
10.30 - 11.00
Coffee break and poster viewing
11.00 - 11.15
Closing session
Chairpersons Dr. Pedro A. Lazo and Dr. Carlos Camps
Awards
ASEICA AND EACR prizes to best communications
“1st ASEICA Young Investigator Award”
“1st ASEICA Cancer Research Award”
11.15 - 12.45
Closing lectures
11.15 - 12.00
Connecting intestinal stem cells to colorectal cancer
Dr. Eduard Batlle, Institut de Recerca Biomèdica (IRB), Barcelona
12.00 - 12.45
EACR Lecture
Targeting K-Ras signaling in cancer
Dr. Mariano Barbacid, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid
13.00 - 13.30
ASEICA general assembly
15th ASEICA
INTERNATIONAL
CONGRESS
Organized by
With the special support of
SPONSORS
Platinum
Gold
Silver
Bronze
Under the auspices of
Accreditation requested to the Spanish System of Continuing Medical Education
Accreditation granted to the European Accreditation Council for continuing
Medical Education (EACCME-ACOE) for 12 European CME credits.
Technical Secretariat · TACTICS
Passatge Batlló 15, 08036 Barcelona - Tlf: 93 451 17 24 - [email protected]