1. Healthcare

Recruitment campaign for professor-researchers - 2015
UPMC - Université Pierre et Marie Curie - Sorbonne Universités
INFORMATION ABOUT THE POSITION
Position number
28 MCF 0464 (4293)
Relevant department
DEPARTMENT OF LIFE SCIENCES
Position type
Associate Professor (Article 26-I-1)
Location
Jussieu Campus
CNU Sections
65 - Cell biology
28 - Dense environments and
materials
TITLE AND SUMMARY OF THE POST
Cell physics
Cell Biology/Physics interface in the background of a developing organ or embryo. The general goal is to understand how
cells react to mechanical stimuli, to identify cellular processes modified by stress and the potential signalling pathways
relaying mechanical input.
EURAXESS RESEARCH FIELD
Biological sciences
Biology
TEACHING
Relevant teaching topics
The successful applicant will help teach first-year and Life Sciences major courses as part of the
Biology-Geosciences-Chemistry (BGC) portal, as well as the Cell and Molecular Biology master’s specialty.
Teaching objectives and supervisory requirements
He or she will help teach the mandatory cell biology and developmental biology courses to first-, secondand third-year students. He or she may also help teach the new optional Biophysics courses for secondand third-year students, as well as teaching biophysics as part of the Cell and Molecular Biology master’s
specialty.
The candidate will be responsible for teaching in a variety of formats, including classes, directed work or
practical work, and will also be responsible for supervising research projects and tutorials for undergraduate
and master’s students.
He or she will also dedicate a significant amount of teaching time to the Career Guidance and Workforce
Readiness modules as well as to the first-year student research projects.
The Associate Professor will also help to teach Cell Biology and Physics at UPMC. In addition, there is the
possibility of creating a master’s program in Cellular Physics to which the candidate could contribute.
RESEARCH
The Associate Professor will join Michel Labouesse’s team (http://www.ibps.upmc.fr/fr). The recruited
Associate Professor will have his or her own project that complements existing research being conducted by
the current team, who are interested in the role of mechanistic constraints in embryonic morphogenesis. He
or she will also contribute to teaching quantitative biology as part of the Biology department.
Although the importance of mechanical forces in biology is well-accepted, we still do not fully understand
how they act in vivo. In particular, our understanding of the range of possible cellular responses to
mechanical force, mechano-sensory mechanisms or attenuation and memory mechanisms is incomplete.
One of the main goals of the team is to define how tensile mechanical force influences the remodeling of the
cytoskeleton and junctions.
We primarily use embryos from the nematode C. elegans, which can stretch by a factor of 4 by deforming its
cells through a process that requires close mechanical coupling of the muscles and the epidermis.
Specifically, the epidermal actin cytoskeleton and microtubules shorten around the circumference, while the
junctions become longer along the anterio-posterior axis. The experimental approaches that will be
developed to explore this question include genetic screens (RNAi and mutagenesis) under designed
conditions, in vivo imaging (spinning-disk, FRAP, FRET) using cytoskeletal and junction markers
(LifeAct::mKate2, CAP::GFP, EB1::GFP, E-Cad::GFP), laser nano-ablation methods, biosensors and
molecular approaches. Longer term goals include defining how the cytoskeleton regulates the elastic
properties of the epidermis and identifying interactions between the epidermis and the muscles (which also
stretch).
The candidate will either have a profound knowledge of key concepts in cell biology, specifically in the
context of animal development, and a good understanding of biophysics, or vice versa. A good
understanding of current quantification methods is important.
HOST LABORATORY
UMR 7622 - Developmental Biology Paris-Seine
FR 3631 - Institute of Biology Paris-Seine
CONTACTS
Research
Michel LABOUESSE (IBPS/FR3631 et UMR7622)
E-mail: [email protected]
Teaching
Hélène POUZET
E-mail: [email protected]
Joëlle SOBCZAK
E-mail: [email protected]
Pedro BAUSERO
E-mail: [email protected]
MANDATORY INSTRUCTIONS FOR PREPARING YOUR APPLICATION
As UPMC has opted for a paperless application procedure, please ensure that you follow the instructions below
exactly to facilitate optimal handling of your application.
Candidate registration will involve two steps:
● 1st step: from 10 am Monday, February 2, 2015 to 4 pm Tuesday, March 10, 2015
REGISTER your candidacy using the GALAXIE application, which can
link: https://galaxie.enseignementsup-recherche.gouv.fr/antares/can/astree/index.jsp
be
found
at
the
following
● 2nd step: from 10 am Monday, February 2, 2015 to midnight on Tuesday, March 10, 2015
REGISTER AND UPLOAD ALL FILES for your application at the following link: http://concours.upmc.fr
The application must contain the following items, according to the current regulations (decrees of October 7, 2009), in PDF
format:
1. a dated and signed declaration of candidacy, which can be downloaded on GALAXIE;
2. a clear copy of photo identification, front and back;
3. a curriculum vitae (cf. article 10 of title IV of the decree of October 7, 2009);
4. a diploma: doctorate, HDR (habilitation à diriger des recherches) or equivalent;
5. the thesis committee report approving the thesis defense/viva;
6. at least one representative example of the work, publications, articles and achievements cited in the CV;
7. additionally, for candidates who are applying in these cases:
7a) as a transfer: certification from the original institution confirming the quality of the professor or lecturer and active
performance of the duties associated with the position for at least three years by the closing date for applications;
7b) for a secondment: recent certification from the current employer citing which category the candidate falls into as
outlined by article 58-1 of decree No. 84-431 of June 6, 1984 concerning the status of research professors and the
quality of the position holder in the context of the original position for at least three years at the closing date for
applications;
7c) as a professor-researcher who holds a similar position in a country other than France that is equivalent to
the advertised position and is therefore exempt from evaluation based on the list of qualifications: recent
certification from the current employer citing the institution that the candidate belongs to, the duration of
employment and the level of duties performed;
7d) under article 46-3: certification from the original employer establishing the quality of the full professor or associate
professor as regulated by decree No. 84-431, modified on June 6, 1984, and the duration of employment, in
accordance with article 46-3 of the aforementioned decree.
Administrative documents in foreign languages must be translated into French.
All relevant information regarding the professor-researcher recruitment can be found on the UPMC website
at the following address, under the heading ACTUALITES (NEWS): http://www.upmc.fr
If you have any questions, you can contact the administrative team at [email protected].
PAPER APPLICATIONS WILL NOT BE ACCEPTED